Blood Testing Apparatus Platelet Detection Accuracy

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Solution Overview

Problem

Existing blood testing methods face challenges in accurately detecting low platelet counts due to the small number of platelets, leading to inaccurate results in routine PLT-I detection.

Innovation Solution

The method involves preparing a second test solution from the remaining first test solution when the initial platelet detection result is below a preset threshold, increasing the statistical amount passing through the impedance detection area for re-detection, or using an optical RET detection area with an increased sample amount for improved accuracy.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If the statistical amount of test solution passing through the impedance detection area is increased, then the detection accuracy of platelets is improved, but the testing time is extended

Engineering Contradiction:
Improveplatelet detection accuracyVSAvoidtesting time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The system performs preliminary platelet detection using a first statistical amount of test solution to obtain initial detection results. Based on these preliminary results, it determines whether low platelet count information exists, and only then increases the statistical amount for re-detection. This preliminary action avoids unnecessary extended testing time while ensuring accurate detection when needed.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The system dynamically adjusts the statistical amount of test solution based on the detection results. When low platelet count is detected, it automatically increases the statistical amount from the first to the second value. When normal platelet count is detected, it maintains the original statistical amount. This dynamic adjustment optimizes both detection accuracy and testing time.

Inventive Principle:
Principle #15Dynamics

2Measurement precision

If the statistical amount of test solution is increased to improve detection accuracy, then the manufacturing cost and usage cost are increased

Engineering Contradiction:
Improveplatelet detection accuracyVSAvoidtest solution consumption
Core Design Contradiction:
Measurement precisionVSQuantity of substance

Solution Approach 1:

The system performs preliminary detection with a smaller statistical amount first to identify samples with low platelet counts. Only for these specific samples does it increase the statistical amount for re-detection. This approach minimizes overall test solution consumption while ensuring accurate detection for problematic samples.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The system automatically determines whether low platelet count information exists based on the first detection results, and self-adjusts the statistical amount accordingly. This self-service mechanism eliminates the need for manual intervention and optimizes resource usage by increasing statistical amount only when necessary.

Inventive Principle:
Principle #25Self-service

3Measurement precision

If the first statistical amount of test solution is increased to ensure accurate detection, then the detection efficiency is reduced

Engineering Contradiction:
Improveplatelet detection accuracyVSAvoiddetection efficiency
Core Design Contradiction:
Measurement precisionVSProductivity

Solution Approach 1:

The system performs preliminary detection with the first statistical amount to quickly identify samples requiring further analysis. This two-stage approach maintains high detection efficiency for normal samples while ensuring accurate detection for low platelet count samples through subsequent re-detection with increased statistical amount.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The system dynamically adjusts the statistical amount based on real-time detection results. For the majority of samples with normal platelet counts, it maintains the original statistical amount for efficient processing. Only for samples showing low platelet count does it increase the statistical amount, thereby optimizing overall detection efficiency.

Inventive Principle:
Principle #15Dynamics

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach enhances the accuracy of platelet detection for low platelet counts by re-conducting the test with a larger sample amount, reducing manufacturing and usage costs while maintaining high detection precision, especially for instruments without optical channels.

Implementation Method 1

performing platelet detection on the first test solution by using an impedance method in the impedance detection area

Methodology Applied
Scientific EffectImpedance method: Electrical Resistance

Implementation Method 2

performing optical detection on the second test solution in the RET detection area to obtain an RET detection result and a second platelet detection result

Methodology Applied
Scientific EffectOptical detection: Scattering

Data Source

PatentUS20240374177A1Blood testing method and apparatus
Publication Date: 2024.11.14 SHENZHEN MINDRAY BIO MEDICAL ELECTRONICS CO LTD
  • US20240374177A1 patent drawing
  • US20240374177A1 patent drawing
  • US20240374177A1 patent drawing

AI summary

A blood detection method and a blood detection device are disclosed. When a count number of platelet in a blood sample is less than a predetermined value, a detection solution of the blood sample is prepared. A cell statistical amount of the detection solution of the blood sample is increased to obtain the platelet detection result. The cell statistics amount of the detection solution of the blood sample may be increased in an impedance detection area to perform PLT-I detection, or in an RET detection area; or performing both of RET detection and PLT-O detection simultaneously. Thus, the accuracy of platelet detection can be improved when the number of platelets in the blood sample is low.