Blood Type Prediction Using Parental Allele Matrices

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Solution Overview

Problem

Current methods for determining a child's blood type are complex, time-consuming, and often require the child to be born before testing can be performed, with limited understanding among the general public about the significance of blood type and its estimation.

Innovation Solution

A system and method for predictive blood type analysis using a processor to generate matrices and vectors based on dominant-recessive allele pairs, applying Punnett square tables to calculate probability rates for each possible blood type of a child, enabling expecting parents to determine their child's blood type and potential health implications.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If laboratory tests are performed during infancy to determine blood type, then accurate blood type determination is achieved, but the process is time-consuming and requires waiting until after the child is born

Engineering Contradiction:
Improveblood type determination accuracyVSAvoidtime to determine blood type
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The system performs preliminary blood type prediction by analyzing parental allele pairs and generating probability distributions before the child is born. This allows expecting parents to know the child's blood type in advance, eliminating the need to wait until infancy for laboratory testing while maintaining accurate determination through computational analysis of genetic inheritance patterns.

Inventive Principle:
Principle #10Preliminary action

2Measurement precision

If comprehensive laboratory testing and interviews are conducted to generate accurate blood type profile, then measurement precision is improved, but device complexity and ease of operation deteriorate

Engineering Contradiction:
Improveblood type profile accuracyVSAvoidtesting process complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The system extracts only the essential genetic information needed for blood type determination - specifically the allele pairs from parental blood types. By focusing solely on this critical data and using computational algorithms to process it, the system eliminates the need for complex laboratory testing procedures, multiple interviews, and extensive medical record reviews, thereby simplifying the process while maintaining accuracy.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The system replaces the mechanical and manual processes of laboratory testing, physical interviews, and record compilation with an automated computational system. The processor executes algorithms that analyze parental allele pairs and generate blood type predictions, substituting complex manual procedures with efficient digital computation that maintains precision while reducing operational complexity.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Loss of information

If extensive interviews and medical record reviews are conducted to determine blood type, then information completeness is improved, but ease of operation and time efficiency worsen

Engineering Contradiction:
Improveblood type information completenessVSAvoidblood type determination ease
Core Design Contradiction:
Loss of informationVSEase of operation

Solution Approach 1:

The system extracts only the critical genetic information from parental blood types that is sufficient to determine all possible blood type outcomes for their child. By identifying and processing only these essential allele pairs through computational analysis, the system achieves complete blood type information without requiring extensive interviews or comprehensive medical record reviews, thereby greatly simplifying the operational process.

Inventive Principle:
Principle #2Taking out (Extraction)

Data Source

PatentUS20230129886A1Systems and methods of blood-type predictive analysis
Publication Date: 2023.04.27 CARTER JOAUNA Z
  • US20230129886A1 patent drawing
  • US20230129886A1 patent drawing
  • US20230129886A1 patent drawing

AI summary

Computer systems and methods of predictive analysis can be instrumental when expecting parents want to know their child's blood type. In some embodiments, the system described herein may include a processor coupled to memory, wherein the processor is operable to receive information about each parent's blood type, including the dominant-recessive allele pairs. This system can generate a first matrix of a plurality of dominant-recessive allele pairs corresponding to both parents including statistics for all combinations of the dominant-recessive allele pairs. Further, the system can generate a second matrix for all possible parental blood type pairings including the relative weights of probability associated with each blood type. In some embodiments, the system can generate a row vector specific to both parent's blood type. As output, the system can generate and display a probability rate corresponding to each possible blood type of a child and blood donor matching.