Artificial Blood Vessel Internal Coating Device
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Solution Overview
Problem
Conventional methods fail to uniformly coat the inside of artificial blood vessels with bioactive substances, leading to inadequate attachment to surrounding tissues and increased risk of complications like bleeding during hemodialysis.
Innovation Solution
A device featuring a guide rail, lifting member, semicircular grooves for secure support, and a coating liquid injection tube with a nozzle tip that injects a bioactive mixture, ensuring uniform coating within the artificial blood vessel lumen while preventing external contact.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Manufacturing precision
If conventional coating liquid delivery methods are used, then the coating process can be performed, but uniform coating formation inside the artificial blood vessel cannot be achieved
Solution Approach 1:
The artificial blood vessel is divided into multiple sections along its length, with the coating process applied segmentally through the injection tube that can move along the vessel. The semicircular grooves segment the support structure to accommodate the vessel while allowing precise positioning and movement of the coating application point.
Solution Approach 2:
A carrier liquid is introduced as an intermediary medium to deliver the coating substance uniformly inside the artificial blood vessel. The carrier liquid flows through the injection tube and distributes the coating material evenly along the vessel interior surface, achieving uniform coating without direct contact application.
2Reliability
If bioactive substance is coated on artificial blood vessel to inhibit neointimal hyperplasia, then angiostenosis and inflammation are reduced, but myofibroblast expansion is suppressed leading to poor tissue attachment
Solution Approach 1:
Different regions of the artificial blood vessel receive different treatments: the inner luminal surface is coated with bioactive substances to prevent angiostenosis and inflammation, while the outer surface remains uncoated or receives different coating to allow myofibroblast expansion and tissue attachment. This spatial differentiation of coating properties resolves the contradiction between preventing complications and ensuring secure attachment.
3Manufacturing precision
If coating liquid is delivered to inside of lumen, then the inside surface can be coated, but uniform film formation is very difficult to achieve
Solution Approach 1:
A carrier liquid is used as a hydraulic medium to deliver the coating substance uniformly through the injection tube. The liquid flow dynamics ensure even distribution of coating material along the vessel interior, achieving uniform film formation through fluid mechanical principles rather than direct mechanical application.
Solution Approach 2:
The physical parameters of the coating delivery system are optimized: the injection tube diameter, carrier liquid flow rate, and coating substance concentration are carefully controlled to achieve uniform coating. The movement speed of the injection tube along the vessel and the pressure parameters of the carrier liquid flow are adjusted to ensure consistent coating thickness throughout the process.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The device achieves a uniform bioactive coating inside artificial blood vessels, enhancing their attachment to surrounding tissues and reducing complications such as bleeding during implantation.
Implementation Method 1
a coating liquid and a gas to be injected through the nozzle tip
Implementation Method 2
a coating liquid and a gas to be injected through the nozzle tip
Data Source
AI summary
The present invention relates to a device for coating the inside of an artificial blood vessel and, to explain more specifically, to a device for coating the inside of an artificial blood vessel inserted into the body of a human for a medical purpose, which is configured to be able to selectively coat just the inside of a lumen of the artificial blood vessel with a bioactive substance for inhibiting neointimal hyperplasia, in order to prevent a side effect, such as angiostenosis or inflammation, from occurring in an area connecting the artificial blood vessel and a blood vessel in the body.