Blood Vessel Positioning for Non-Invasive Optical Glucose Testing

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Solution Overview

Problem

Existing medical imaging technologies struggle to accurately distinguish between blood vessels and surrounding skin areas for glucose testing, particularly in individuals with different skin colors, leading to inaccurate test results and the need for invasive methods.

Innovation Solution

A method and system utilizing infrared and ultraviolet light to irradiate a body surface, image grayscale areas, and collect fluorescence radiation signals to accurately identify venous blood vessels, enabling non-invasive glucose testing.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If traditional optical testing method is used, then the testing process is simple, but the test result is inaccurate because blood vessels cannot be accurately distinguished from skin areas

Engineering Contradiction:
Improveaccuracy of glucose test resultVSAvoidcomplexity of imaging and positioning system
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent segments the imaging process into multiple wavelength components (infrared for blood vessel positioning, visible light for skin imaging, ultraviolet for fluorescence excitation). This segmentation allows each wavelength to perform its specific function optimally, with infrared specifically targeting blood vessels to distinguish them from surrounding skin, thereby improving measurement precision without requiring a single complex multi-functional device

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent introduces infrared light as an intermediary to indirectly detect and position blood vessels before performing the actual glucose measurement. This intermediary step enables accurate identification of blood vessel locations, which then guides the subsequent visible light and ultraviolet imaging processes to focus on the correct areas, improving test accuracy while maintaining systematic organization

Inventive Principle:
Principle #24Intermediary (Mediator)

2Ease of operation

If electrochemical method is used, then blood vessel positioning is not needed, but the testing method becomes invasive

Engineering Contradiction:
Improvenon-invasive testing capabilityVSAvoidaccuracy of glucose measurement in blood vessels
Core Design Contradiction:
Ease of operationVSMeasurement precision

Solution Approach 1:

The patent replaces the mechanical/invasive electrochemical needle insertion with an optical system that uses infrared, visible, and ultraviolet light to non-invasively detect and measure glucose in blood vessels. The optical method substitutes physical penetration with light-based detection, achieving both non-invasive operation and accurate blood vessel targeting through multi-wavelength imaging

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent changes the detection parameter from electrical chemical reactions (electrochemical method) to optical properties across multiple wavelengths (infrared absorption, visible light reflection, ultraviolet fluorescence). This parameter change enables non-invasive measurement while maintaining the ability to specifically target blood vessels through their unique optical characteristics at different wavelengths

Inventive Principle:
Principle #35Parameter changes

3Measurement precision

If visible light is used for blood vessel positioning, then the system is simple, but positioning accuracy deteriorates in individuals with darker skin colors

Engineering Contradiction:
Improveaccuracy of blood vessel positioningVSAvoidadaptability to different skin colors
Core Design Contradiction:
Measurement precisionVSAdaptability or versatility

Solution Approach 1:

The patent transitions from using only visible light (two-dimensional color-based detection) to incorporating infrared wavelength (adding a third dimensional parameter). Infrared radiation penetrates skin differently and is less affected by melanin content, providing an additional detection dimension that enables accurate blood vessel positioning across all skin colors, not just lighter skin tones

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

Solution Approach 2:

The patent changes the detection parameter from visible light wavelength to infrared wavelength for blood vessel positioning. This parameter change exploits the different interaction between infrared radiation and skin pigmentation, allowing consistent blood vessel detection regardless of skin color variations, thereby improving both positioning accuracy and adaptability to diverse populations

Inventive Principle:
Principle #35Parameter changes

4Measurement precision

If pyramid optical flow tracing method is used, then blood vessel positioning accuracy is improved, but the system cannot address skin color variations

Engineering Contradiction:
Improveaccuracy of blood vessel position determinationVSAvoidcapability to handle different skin colors
Core Design Contradiction:
Measurement precisionVSAdaptability or versatility

Solution Approach 1:

The patent creates a universal blood vessel positioning system that functions across all skin colors by combining infrared imaging (for blood vessel detection independent of skin color) with visible light imaging (for skin surface reference). This multi-functional approach makes the system universally applicable to all populations regardless of skin pigmentation, overcoming the limitation of skin-color-specific methods

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The patent introduces infrared imaging as an intermediary that mediates between the skin surface appearance (visible light) and the underlying blood vessel structure. This intermediary infrared channel provides blood vessel information that is independent of skin color, allowing the optical flow tracing algorithm to work universally across different skin tones by using infrared-derived vessel positions rather than relying solely on visible light intensity variations

Inventive Principle:
Principle #24Intermediary (Mediator)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Accurate positioning of blood vessels in various skin colors, reducing labor costs, and enabling non-invasive glucose testing with real-time, low-cost, and miniaturized systems.

Implementation Method 1

irradiating a first area of a body surface by infrared light, and imaging the first area

Methodology Applied
Scientific EffectInfrared radiation: Infrared Radiation

Implementation Method 2

irradiating the area in which the target is located and the area in which the non-target is located by ultraviolet light, and respectively collecting fluorescence radiation signals excited in the area in which the target is located and the area in which the non-target is located

Methodology Applied
Scientific EffectFluorescence: Fluorescence

Data Source

PatentEP4681607A1Method and system for target positioning analysis, medium, and device
Publication Date: 2026.01.21 SENSURA PTE LTD
  • EP4681607A1 patent drawingFigure 1~2
  • EP4681607A1 patent drawingFigure 3~4
  • EP4681607A1 patent drawingFigure 5~6

AI summary

The present invention provides a method and system for target positioning analysis, a medium, and a device. The method includes: irradiating and imaging a first area of a body surface by infrared light, to obtain a first image of an imaging area; dividing the imaging area into different grayscale areas; selecting a grayscale area whose grayscale value meets preset requirements as an area in which a blood vessel is located; selecting, from an edge of the area in which the blood vessel is located, a grayscale area as an area in which skin is located; and irradiating the area in which the blood vessel is located and the area in which the skin is located, and respectively collecting fluorescence radiation signals excited in the area in which the blood vessel is located and the area in which the skin is located.