Blower Fan Bias Flow Control for Indirect Calorimetry

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Solution Overview

Problem

Existing indirect calorimetry methods face challenges in accurately measuring energy expenditure due to difficulties in adjusting bias flow, which can lead to incomplete gas capture and require significant operator skill, especially with open face tent collection methods.

Innovation Solution

A computerized bias-flow control algorithm that electronically adjusts the speed of a blower fan to ensure all exhaled carbon dioxide is captured, using a face mask connected to a pneumotach flow meter and oxygen, carbon dioxide, and flow measurement system, with software controlling the fan speed in real-time to match respiratory flow.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If manual bias flow adjustment is used in open face tent collection, then operator control flexibility is maintained, but measurement accuracy deteriorates due to incomplete gas capture and operator error

Engineering Contradiction:
Improveenergy expenditure measurement accuracyVSAvoidoperator skill requirement
Core Design Contradiction:
Measurement precisionVSEase of operation

Solution Approach 1:

The patent replaces the manual mechanical adjustment system (operator turning potentiometer to control fan speed) with an electronic automated control system. A microprocessor-based controller automatically adjusts the bias flow fan speed based on real-time measurements from flow sensors and gas concentration sensors, eliminating the need for manual mechanical adjustment and thereby improving measurement accuracy while reducing operator skill requirements.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent implements a closed-loop feedback control system where sensors continuously monitor expiratory gas flow and CO2 concentration, and this information is fed back to the microprocessor controller. The controller automatically adjusts the bias flow fan speed based on this feedback to maintain optimal conditions for complete gas capture, ensuring accurate energy expenditure measurements without requiring operator intervention.

Inventive Principle:
Principle #23Feedback

2Measurement precision

If high bias flow is used to ensure complete gas capture, then measurement accuracy improves, but patient comfort deteriorates due to elevated CO2 and depressed oxygen levels

Engineering Contradiction:
Improvegas capture completenessVSAvoidelevated CO2 level and depressed oxygen level
Core Design Contradiction:
Measurement precisionVSObject-affected harmful factors

Solution Approach 1:

The patent employs a dynamic bias flow control system where the fan speed is continuously adjusted based on real-time measurements of patient respiratory flow and gas concentrations. Rather than maintaining a constant high bias flow, the system dynamically adapts the flow rate to match patient needs, ensuring complete gas capture during expiration while minimizing the duration and intensity of elevated CO2 exposure, thereby improving both measurement accuracy and patient comfort.

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The patent changes the bias flow parameter dynamically during the measurement process. The microprocessor controller adjusts the fan speed (bias flow rate) based on measured respiratory patterns and gas concentrations, optimizing the balance between complete gas capture for accurate measurement and maintaining acceptable gas composition for patient comfort and safety.

Inventive Principle:
Principle #35Parameter changes

3Reliability

If rigid total collection system is used, then gas capture reliability improves, but time to reach steady state increases

Engineering Contradiction:
Improvegas capture reliabilityVSAvoidtime to reach steady state
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The patent replaces the rigid static collection system with a dynamic adaptive system. The bias flow fan speed is continuously adjusted in real-time based on patient respiratory patterns and gas concentration measurements, allowing the system to quickly adapt to changing conditions and reach steady state faster while maintaining reliable gas capture throughout the measurement process.

Inventive Principle:
Principle #15Dynamics

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach ensures accurate measurement of resting energy expenditure by maintaining a consistent and sufficient bias flow, reducing operator error and the time required to reach steady state, while maintaining patient safety and comfort.

Implementation Method 1

Bias flow was achieved by a battery-powered fan with an operator adjusted potentiometer to control the speed of the fan

Methodology Applied
Scientific EffectBias flow:

Implementation Method 2

pneumotach flow meter whose output is coupled to a vacuum inlet of an electric motor driven blower fan

Methodology Applied
Scientific EffectPressure drop: Pressure Drop

Implementation Method 3

In indirect calorimetry, oxygen consumption and/or carbon dioxide production is measured and converted to energy expenditure using an experimentally-derived formulae

Methodology Applied
Scientific EffectIndirect calorimetry: Calorimetry

Implementation Method 4

measure CO2 production and O2 uptake as a cross product integration of the flow and the measured percentages of CO2 and O2

Methodology Applied
Scientific EffectCross product integration:

Data Source

PatentUS10271788B2Apparatus and method for measuring energy expenditure using indirect calorimetry
Publication Date: 2019.04.30 MGC DIAGNOSTICS CORP
  • US10271788B2 patent drawing
  • US10271788B2 patent drawing
  • US10271788B2 patent drawing

AI summary

The present invention describes an apparatus and method for determining the energy expenditure of a subject by indirect calorimetry where respiratory gases O2 and CO2 are captured in a tent mask coupled through a pneumotach flow meter to a vacuum inlet of a blower fan whose speed is controlled by a computer running a program that ensures that the bias flow being drawn through the mask always exceeds the subject's peak expiratory flow. VO2 and VCO2 and flow values are measured on a breath-by-breath basis and used in arriving at a bias flow adjustment voltage to be applied to the blower fan for adjusting its speed.