Blue Fish Protein Hydrolysate for Cognitive Decline
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
There is a lack of products on the nutraceutical and pet food markets that effectively utilize eco-friendly processes to provide significant amounts of bioactive ingredients like DHA, EPA, and phospholipids from blue fish for preventing age-related cognitive decline in humans and animals.
Innovation Solution
A protein hydrolyzate derived from blue fish, specifically with a degree of hydrolysis of at least 10%, containing at least 80% water-soluble proteins with a molecular weight less than 1000 Da, 0.3% phospholipids, and 0.5% DHA and EPA, is developed, along with a process involving grinding, pH adjustment, enzyme addition, heating, separation, and drying to create a bioactive peptide-rich composition.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Loss of substance
If conventional fish processing methods are used, then fish byproducts are discarded or underutilized, but significant amounts of bioactive ingredients (DHA, EPA, phospholipids) are wasted
Solution Approach 1:
The patent extracts bioactive ingredients (DHA, EPA, phospholipids, proteins) from blue fish byproducts through a systematic processing approach. The method separates and concentrates these valuable components from the fish matrix, transforming waste material into a functional hydrolyzate product with specific compositional requirements (≥0.5% DHA+EPA, ≥0.3% phospholipids, ≥80% water-soluble proteins <1000 Da).
Solution Approach 2:
The patent applies controlled parameter changes during processing, specifically adjusting pH levels and temperature conditions to optimize the extraction and hydrolysis of bioactive compounds. The degree of hydrolysis is controlled to achieve the desired molecular weight distribution of proteins, ensuring maximum bioactivity while maintaining process efficiency.
2Quantity of substance
If blue fish byproducts are fully utilized through hydrolysis, then bioactive peptide content increases, but the process requires multiple steps (grinding, pH adjustment, enzyme addition, heating, separation, drying)
Solution Approach 1:
The patent segments the hydrolysis process into distinct operational phases: grinding the fish byproducts, adjusting pH to optimal levels, adding specific enzymes, controlled heating, separation of components, and drying. This segmentation allows each step to be optimized independently while maintaining overall process efficiency and product quality consistency.
Solution Approach 2:
The patent uses pH adjustment and enzyme addition as intermediary steps to facilitate the hydrolysis reaction. These intermediaries enable controlled breakdown of proteins into bioactive peptides without requiring extreme conditions, and the separation step acts as an intermediary to isolate the desired bioactive components from the reaction mixture.
3Stability of the object's composition
If a standardized hydrolyzate product is produced with specific compositional requirements, then product quality and consistency improve, but manufacturing precision and control are required
Solution Approach 1:
The patent implements compositional control through monitoring and adjustment during processing. The degree of hydrolysis, protein solubility, and bioactive compound content are controlled to meet specific specifications (≥80% water-soluble proteins <1000 Da, ≥0.5% DHA+EPA, ≥0.3% phospholipids), ensuring consistent product quality across batches.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The blue fish hydrolyzate demonstrates neuroprotective effects, improves cognitive abilities, and reduces stress/anxiety, serving as a preventative and therapeutic agent for age-related cognitive decline in both humans and animals.
Implementation Method 1
a protein hydrolyzate obtained from at least one protein source from blue fish comprising (i) a degree of hydrolysis (DH) of at least 10%
Implementation Method 2
heating, separation, and drying to create a bioactive peptide-rich composition
Implementation Method 3
separation
Data Source
Figure 1a
Figure 1b
Figure 1c
AI summary
The invention relates to a protein hydrolysate which is obtained from at least one protein source derived from blue-backed fish and which comprises (i) a degree of hydrolysis (DH) of at least 10%, (ii) at least 80% water-soluble proteins having a molecular weight of less than 1000 Da, (iii) at least 0.3% phospholipids, and (iv) at least 0.5% DHA and EPA.