Calibration Method for Bodily-Fluid Component Measurement Device
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
The existing body fluid component measuring instruments, such as blood glucose meters, face challenges in achieving accurate measurements due to optical axis deviations in the measurement optical system, which require precise mounting accuracy and increase manufacturing costs.
Innovation Solution
A calibration method and system that measures the offset of the reflection point on the test strip's measurement surface to calculate a correction light quantity, allowing for the determination of a calibration curve that cancels changes in detection light quantity attributed to surface reflection light, thereby ensuring accurate measurements without requiring precise mounting accuracy of the measurement optical system.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Ease of manufacture
If mounting accuracy of the measurement optical system is not precisely controlled, then manufacturing costs are reduced, but measurement accuracy deteriorates due to optical axis deviation
Solution Approach 1:
The patent applies preliminary action by measuring the offset of the reflection point on the measurement surface before performing the actual measurement. This offset measurement is done in advance to determine the necessary correction light quantity, allowing the system to pre-compensate for optical axis deviations without requiring precise mounting accuracy. The calibration curve is determined beforehand based on the measured offset, so when actual measurements are taken, the correction is already built into the measurement process.
Solution Approach 2:
The patent changes the parameter of detection light quantity by adding or subtracting a correction light quantity based on the measured offset. Instead of trying to maintain a fixed optical path, the system dynamically adjusts the detection light quantity parameter to compensate for deviations. This allows the measurement system to tolerate variations in mounting accuracy while maintaining measurement precision through parameter adjustment.
2Measurement precision
If mounting accuracy of the measurement optical system is precisely controlled, then measurement accuracy is improved, but manufacturing time and costs increase
Solution Approach 1:
The patent replaces the mechanical approach of ensuring precise mounting accuracy with an optical/electronic compensation approach. Instead of mechanically controlling the optical system's position through precise mounting, the system uses optical measurement of the reflection point offset and electronic calculation of correction light quantity to compensate for deviations. This substitution eliminates the need for time-consuming precision mounting operations while maintaining measurement accuracy.
3Measurement precision
If mounting accuracy of the measurement optical system is precisely controlled, then measurement accuracy is improved, but manufacturing costs increase
Solution Approach 1:
The patent applies self-service by enabling the measurement system to automatically detect and compensate for its own optical axis deviations. The system measures the reflection point offset on the measurement surface, calculates the appropriate correction light quantity, and adjusts the detection accordingly. This self-compensation mechanism eliminates the need for expensive precision mounting and external calibration procedures, allowing the system to maintain high measurement accuracy while reducing manufacturing costs.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This approach enables accurate measurement of body fluid components by compensating for optical path deviations, improving measurement accuracy and reducing manufacturing costs by eliminating the need for precise mounting accuracy of the measurement optical system.
Implementation Method 1
a measurement optical system for projecting light on a measurement surface of a test strip that contains a chromogenic reagent that reacts with a component in a body fluid and detecting reflected light
Implementation Method 2
a test strip impregnated with a reagent that develops color corresponding to the amount of glucose in the blood
Data Source
Figure 1
Figure 2
Figure 3
AI summary
The present invention relates to a calibration method, calibration system, and a body fluid component measuring instrument calibrated by using the same method. An offset of a reflection point (R) on the measurement surface (54) is measured. The offset represents a deviation amount of an actual optical path (Lr) of the measurement optical system (40) with respect to a reference optical path (Ls) of the measurement optical system (40). The measurement optical system (40) is mounted on the calibration target instrument (10c) that is a body fluid component measuring instrument (10) as a calibration target. Based on the measured offset, a correction light quantity to be uniformly added or subtracted to/from the detection light quantity is calculated. Based on the calculated correction light quantity, a calibration curve for the calibration target instrument (10c) is determined.