Water-Free Bone Cement Paste for High Compressive Strength
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Solution Overview
Problem
Current mineral bone cements, particularly calcium phosphate cements, face challenges in achieving high compressive strength while maintaining a short curing time and storage stability in a water-free, paste-like form, which is essential for producing implants with improved mechanical properties.
Innovation Solution
A preparation comprising mineral cement powder with calcium or magnesium ions, a sparingly water-soluble organic carrier liquid, and a combination of anionic and nonionic surfactants, with a specific weight ratio of solids to carrier liquid and surfactants, that hardens upon contact with water to achieve high compressive strengths exceeding 25 MPa.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Ease of operation
If mineral cement powder is dispersed in a carrier liquid to form a storage-stable paste, then ease of handling and dosing is improved, but the compressive strength of the resulting implant is reduced
Solution Approach 1:
The patent changes the key parameter of water content from the conventional range (significant amounts) to less than 1% by weight. This drastic parameter change enables the paste to maintain storage stability while achieving high compressive strength (>25 MPa) after curing, resolving the contradiction between ease of handling and strength
Solution Approach 2:
The patent creates a composite preparation combining mineral cement powder with a specific mixture of carrier liquid and surfactants. This composite structure allows the paste to remain stable during storage and dosing while achieving high strength upon contact with water during the setting reaction
2Strength
If the solids content in the paste is increased to improve strength, then compressive strength is improved, but the paste becomes less stable during storage
Solution Approach 1:
The patent optimizes the carrier liquid content to a specific range (4-16% by weight) and maintains water content below 1% by weight. These parameter changes enable the paste to maintain stability during storage while achieving high compressive strength after curing, resolving the contradiction between strength and storage stability
3Reliability
If water is added to trigger the setting reaction, then the cement hardens to form the implant, but the curing time increases and strength development is delayed
Solution Approach 1:
The patent uses minimal water (less than 1% by weight in the prepared paste) to initiate the setting reaction. This partial action approach allows the cement to harden efficiently upon contact with body fluids or minimal water addition, reducing curing time while maintaining reliable setting function
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The solution provides a storage-stable, water-free paste that hardens to form implants with compressive strengths of up to 75 MPa, significantly improving upon existing technologies by ensuring high mechanical integrity and stability during storage and use.
Implementation Method 1
Due to the setting reaction triggered by mixing the powder with water, a solid is formed
Implementation Method 2
The use of several surfactants facilitates the incorporation of the solids into the carrier liquid
Implementation Method 3
at least one anionic and at least one nonionic surfactant containing at least one ethoxylated fatty alcohol, at least one ethoxylated fatty acid, at least one ethoxylated sorbitan fatty acid ester, at least one ethoxylated fat or at least one ethoxylated oil
Data Source
Figure 1
AI summary
The invention relates to a preparation for manufacturing an implant, preferably a bone implant, a process for said manufacture and mouldings obtainable therefrom. The preparation comprises the following components: a) mineral cement powder comprising at least one calcium-ion-containing and/or at least one magnesium-ion-containing inorganic compound as a reactive component; b) at least one organic carrier liquid; c) at least two surfactants selected from at least two of the groups of anionic, cationic, amphoteric and nonionic surfactants; d) less than 1% w/w water based on the total mass of the composition, wherein the weight ratio of the total solids present in the formulation solids to the sum of the weight of the organic carrier liquid and the at least two surfactants is more than if the cement powder contains calcium-ion-containing and no magnesium-ion-containing compounds as the reactive component, or is more than 6 if the cement powder contains magnesium-ion-containing or magnesium-ion- and calcium-ion-containing compounds as the reactive component.