Bone Fiber Nanocoating via Segmented Slurry and Mesh Apparatus

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Solution Overview

Problem

Current bone implant coatings fail to penetrate the implant surface uniformly, leading to agglomeration and reduced integration into bone defects due to challenges in applying nanoparticle-sized mineral coatings, which often degrade quickly, compromising the implant's bioactivity and stability.

Innovation Solution

A method and apparatus for coating bone material particles with a mineral coating, utilizing a container system and mesh apparatus to ensure uniform coating of individual fibers, achieving a nanocoating with specific dimensions and geometry that enhances bioactivity and surface area, thereby improving integration and stability.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If nanoparticle-sized mineral coatings are applied to bone implant surfaces, then bioactivity is enhanced, but the coatings agglomerate and degrade quickly

Engineering Contradiction:
ImprovebioactivityVSAvoidcoating stability
Core Design Contradiction:
ReliabilityVSStability of the object's composition

Solution Approach 1:

The coating process is segmented into multiple sequential steps: applying a slurry coating, drying to form a powder layer, then applying additional slurry and drying again. This multi-stage approach prevents agglomeration by building up the coating in controlled increments rather than applying a thick coating all at once, thereby maintaining both bioactivity and stability

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

A preliminary slurry coating is applied and dried to create a stable powder layer before applying the final mineral coating. This preliminary action prepares the surface in advance, providing a stable foundation that prevents subsequent coating degradation and agglomeration while maintaining bioactivity

Inventive Principle:
Principle #10Preliminary action

2Area of moving object

If nanoparticle coatings are applied to bone implants, then surface area is increased, but uniform distribution is difficult to achieve

Engineering Contradiction:
Improvesurface areaVSAvoidcoating uniformity
Core Design Contradiction:
Area of moving objectVSManufacturing precision

Solution Approach 1:

A spray apparatus using pneumatic or hydraulic mechanisms is employed to atomize and distribute the mineral coating slurry uniformly across the bone implant surface. This fluid-based delivery system ensures even distribution of nanoparticles, maximizing surface area while maintaining uniform coating thickness and preventing agglomeration

Inventive Principle:
Principle #29Pneumatics and hydraulics

3Duration of action of stationary object

If the outermost layer degrades, then the nanocoating is lost, but this reduces integration into bone defect

Engineering Contradiction:
Improvenanocoating durabilityVSAvoidbone integration
Core Design Contradiction:
Duration of action of stationary objectVSReliability

Solution Approach 1:

A preliminary slurry coating and drying step creates a stable powder layer that serves as a durable foundation before the final mineral coating is applied. This preliminary action ensures long-term durability of the nanocoating, maintaining its integrity even as the outermost layer degrades, thereby preserving bone integration capability throughout the implant's service life

Inventive Principle:
Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The solution provides a uniformly coated bone implant with increased bioactivity and surface area, enhancing bone remodeling and integration by ensuring each fiber is coated individually, reducing agglomeration and degradation issues, thus improving the implant's longevity and effectiveness.

Implementation Method 1

contacting the plurality of bone material fibers with the mineral coating liquid to coat each individual bone material fiber

Methodology Applied
Scientific EffectAdsorption: Adsorption

Implementation Method 2

coat each individual bone material fiber with the mineral coating liquid to form a plurality of coated bone material fibers

Methodology Applied
Scientific EffectDeposition: Deposition (physical)

Implementation Method 3

The apparatus comprises a first mesh having a first set of openings configured to allow the mineral coating liquid and a plurality of bone material fibers of a select size therethrough

Methodology Applied
Scientific EffectPhysical separation: Filter (physical)

Data Source

PatentUS20240157026A1Methods, compositions and apparatus for coating bone material
Publication Date: 2024.05.16 WARSAW ORTHOPEDIC INC
  • US20240157026A1 patent drawing
  • US20240157026A1 patent drawing
  • US20240157026A1 patent drawing

AI summary

Methods, compositions and apparatus for coating bone material particles (e.g., fibers) are provided. The methods, compositions and apparatus comprise providing a container configured to receive a mineral coating liquid and a plurality of bone material particles (e.g., fibers) therein; adding the plurality of bone material particles (e.g., fibers) to the container; and contacting the plurality of bone material particles (e.g., fibers) with the mineral coating liquid in the container so as to coat each individual bone material particle (e.g., fiber) with the mineral coating liquid to form a plurality of coated bone material particles (e.g., fibers).