Patient-Specific Bone Graft Placement Guides for Mandible Reconstruction

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Solution Overview

Problem

Current orthopedic implant technologies face challenges in creating patient-specific and mass-customized implants that accurately match individual bone anatomy, particularly for deformed, shattered, or missing bone structures, leading to suboptimal fit and functionality.

Innovation Solution

The method involves comparing patient-specific abnormal bone models with reconstructed models to optimize implant parameters, generating electronic design files, and fabricating customized implants using data from statistical atlases and imaging techniques like MRI, CT, and X-ray images, ensuring precise fit and functionality.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Manufacturing precision

If patient-specific abnormal bone models are compared with reconstructed models to optimize implant parameters, then manufacturing precision and fit accuracy are improved, but device complexity and data processing requirements increase

Engineering Contradiction:
Improveimplant fit accuracyVSAvoidmodel comparison system
Core Design Contradiction:
Manufacturing precisionVSDevice complexity

Solution Approach 1:

The system performs preliminary actions by creating reconstructed bone models that represent ideal anatomy before the actual implantation procedure. These pre-computed models serve as templates for optimizing implant parameters, allowing the system to determine the best fit and orientation in advance, thereby improving manufacturing precision without adding complexity to the surgical procedure itself

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The invention creates simplified digital copies (reconstructed models) of the patient's bone anatomy that capture the essential geometric features needed for implant planning. These copied models can be manipulated and compared with implant designs without requiring complex real-time processing of the actual patient anatomy, thus improving fit accuracy while managing system complexity

Inventive Principle:
Principle #26Copying

2Adaptability or versatility

If customized implants are fabricated using statistical atlas data and imaging techniques, then adaptability to individual anatomy is improved, but productivity and manufacturing time increase

Engineering Contradiction:
Improveanatomical matching capabilityVSAvoidimplant fabrication speed
Core Design Contradiction:
Adaptability or versatilityVSProductivity

Solution Approach 1:

The system uses statistical atlas data that represents a universal database of bone anatomy from multiple patients. This universal data structure can be applied to any individual patient case, allowing the same framework and algorithms to handle diverse anatomical variations. The multi-functional nature of the statistical atlas enables adaptability to individual anatomy while maintaining consistent manufacturing processes that preserve productivity

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The invention optimizes implant parameters by comparing patient-specific models with reconstructed models, automatically adjusting size, shape, and orientation parameters to achieve the best fit. This automated parameter optimization reduces manual customization time and streamlines the manufacturing process, thereby improving adaptability without significantly increasing fabrication time

Inventive Principle:
Principle #35Parameter changes

3Reliability

If complete bone reconstruction is performed for deformed or shattered bones, then reliability of implant placement is improved, but measurement precision requirements and data processing increase

Engineering Contradiction:
Improveimplant placement accuracyVSAvoidbone model reconstruction accuracy
Core Design Contradiction:
ReliabilityVSMeasurement precision

Solution Approach 1:

The system introduces reconstructed bone models as intermediary representations between the patient's actual deformed anatomy and the implant design. These intermediary models fill in missing or deformed portions of the bone by referencing statistical atlas data, providing a complete geometric framework for reliable implant placement without requiring ultra-precise measurement of the damaged bone regions themselves

Inventive Principle:
Principle #24Intermediary (Mediator)

Data Source

PatentEP4134046A1Method of designing a patient-specific placement guide
Publication Date: 2023.02.15 MAHFOUZ MOHAMED R
  • EP4134046A1 patent drawingFigure 1~2
  • EP4134046A1 patent drawingFigure 3~4
  • EP4134046A1 patent drawingFigure 5

AI summary

A method of designing one or more bone graft placement guides. The bone graft placement guides are patient-specific and conform to the anatomy of the patient (both donor bone and residual bone to which the donor bone is mounted) to ensure correct placement of the bone graft with respect to the residual bone. In exemplary form, the bone graft placement guide is configured for a mandible bone reconstructive procedure. In order to design the bone graft placement guides, the software utilizes the virtual 3D model of the excised bone applied to the virtual 3D model of the patient's abnormal anatomy to construct a hybrid model. Using this hybrid model, joints are identified where the bone graft will interface with (and hopefully join via bone growth) the adjacent residual bone.At these joints, depending upon various factors, such as surgeon preference, the system identifies bone graft plate locations and, for each plate, one or more guides to facilitate correct placement and securing of the plates to the bone graft and residual bone.