Bone Marrow Image Analysis Device for Remote Diagnosis
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Solution Overview
Problem
Current bone marrow examination methods are inefficient and labor-intensive, requiring extensive expertise and causing eye fatigue, with limited quality control and delayed information delivery due to poor image quality and reliance on microscopic observation and apprenticeship training.
Innovation Solution
A device and method for image analysis that acquires and processes bone marrow images using an imaging device, classifies cells into different classes using a preset algorithm, and provides high-magnification images and discrimination indices, enabling efficient and remote reading without microscopic observation.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If bone marrow reading is performed by microscopic observation requiring substantial experience and knowledge, then diagnostic accuracy is improved, but eye fatigue increases and time consumption increases
Solution Approach 1:
The patent creates digital copies of bone marrow images that can be viewed on screens without requiring continuous microscopic observation. The system captures images and generates digital representations that preserve diagnostic information, allowing multiple experts to review the same case without additional time loss from physical slide handling and microscopic examination.
Solution Approach 2:
The patent replaces the mechanical system of microscopic observation with an image analysis system using algorithms and computer-based image processing. The discrimination index unit automatically analyzes captured images to generate diagnostic information, substituting manual microscopic examination with automated image processing while maintaining diagnostic accuracy.
2Measurement precision
If bone marrow slides are sent by parcel post or courier service for expert consultation, then expert opinions can be obtained, but information delivery is delayed and cannot be provided on the day of examination
Solution Approach 1:
The system creates digital copies of bone marrow images that can be instantly transmitted electronically. Instead of sending physical slides through postal services, the captured images are converted into digital format and can be rapidly shared with other experts or facilities, enabling same-day consultation and significantly accelerating information delivery.
Solution Approach 2:
The patent introduces an image analysis system as an intermediary between bone marrow examination and expert consultation. The discrimination index unit and image processing system serve as a mediator that prepares and transmits diagnostic information in a format suitable for rapid electronic communication, eliminating the need for physical slide transport.
3Ease of manufacture
If only a few stereotypical cell type photographs are provided in atlases, then reference material is available, but comprehensive diagnosis is limited and quality control is insufficient
Solution Approach 1:
The system generates numerous copies of actual bone marrow cell images through automated image capture and processing. Instead of relying on a limited set of stereotypical photographs in atlases, the discrimination index unit produces multiple image copies from actual patient samples, providing comprehensive reference material that reflects real variability in bone marrow cell morphology.
Solution Approach 2:
The patent applies parameter changes by using image processing algorithms to enhance and transform captured images into standardized formats suitable for diagnosis. The discrimination index unit modifies image parameters such as contrast, brightness, and magnification to optimize visual information while maintaining accurate representation of cell morphology, thereby improving diagnostic capability beyond static atlas photographs.
Data Source
AI summary
A device for supporting bone marrow reading based on image analysis includes an image acquisition unit for acquiring a bone marrow image of a subject for bone marrow reading by an imaging device; a discrimination index unit for classifying the acquired bone marrow image into a class among a plurality of classes corresponding to preset discrimination indices; and a result providing unit for providing the result read by the discrimination index unit.