Bone Replacement Material with Ceramic Core and Moldable Mass

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Solution Overview

Problem

Current bone replacement materials face challenges such as limited load-bearing capacity, inability to precisely fit complex bone defects, and difficulty in revising or removing implants, leading to potential implant failure and loosening, especially in joint defects.

Innovation Solution

A bone replacement material composed of a moldable mass and supporting bodies that harden upon contact with water, allowing precise fitting and increased load-bearing capacity, with optional reinforcement by fibers and tension elements, enabling mechanical processing post-hardening for revision operations.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Strength

If ceramic implants are used to treat bone defects, then the mechanical properties become more comparable to natural bone tissue, but the implants cannot be adapted to the shape of the defect or modified during revision surgery

Engineering Contradiction:
Improvemechanical propertiesVSAvoidadaptability to defect shape
Core Design Contradiction:
StrengthVSAdaptability or versatility

Solution Approach 1:

The implant is divided into two functional components: a rigid ceramic core (providing mechanical strength and stability) and a separate malleable mass (enabling adaptation to defect shape). This segmentation allows each component to fulfill its specific function without compromise.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The implant combines ceramic material (for mechanical strength) with a malleable bone substitute material (for shape adaptation). This composite structure integrates the advantages of both materials: the ceramic provides load-bearing capacity while the malleable material enables precise fitting to complex defect geometries.

Inventive Principle:
Principle #40Composite materials

2Strength

If metallic implants are used to bridge bone defects, then the implant can provide structural support, but the transitions from metal to bone are subject to significant fluctuations in stress making long-term fusion difficult

Engineering Contradiction:
Improvestructural supportVSAvoidlong-term fusion
Core Design Contradiction:
StrengthVSReliability

Solution Approach 1:

The implant changes the mechanical parameter of the bridging material from high-strength metal to ceramic with bone-like mechanical properties. This parameter change reduces stress fluctuations at the metal-bone interface and promotes physiological stress distribution, facilitating long-term fusion.

Inventive Principle:
Principle #35Parameter changes

3Ease of manufacture

If bone substitute materials are used to treat bone defects, then the material can be inserted without complex preparation, but the load-bearing capacity is limited and forces may not be sufficiently transferred to healthy bone

Engineering Contradiction:
Improveease of insertionVSAvoidload-bearing capacity
Core Design Contradiction:
Ease of manufactureVSStrength

Solution Approach 1:

The implant combines a rigid ceramic core (for load-bearing capacity) with a malleable bone substitute material (for ease of insertion and adaptation). This composite structure enables both simple insertion without complex bone preparation and sufficient force transfer to healthy bone through the ceramic component.

Inventive Principle:
Principle #40Composite materials

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The material provides improved load-bearing capacity, precise fitting for complex defects, and the ability to be processed mechanically, reducing the risk of implant failure and allowing for effective treatment of both initial and revised bone defects.

Implementation Method 1

a moldable mass which, in an uncured state, enables a precise fitting of the bone replacement material to a bone defect

Methodology Applied
Scientific EffectHardening upon contact with water: Phase Change

Data Source

PatentEP3294357B1Bone replacement materials, method for producing a bone replacement material and medical kits for the treatment of bone defects
Publication Date: 2021.03.17 AESCULAP AG
  • EP3294357B1 patent drawing

AI summary

The invention relates to a bone replacement material which comprises support elements and a plastic mass that can harden upon contact with water or with an aqueous liquid. The invention further relates to a method for producing a bone replacement material, a bone replacement material and medical kits for the treatment of bone defects.