Boron-Free Liquid Enzyme Composition With 1,2-Diol Stabilization
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Solution Overview
Problem
Existing liquid enzyme products face challenges in maintaining microbial and physical stability without the use of preservation agents, which are often undesirable, particularly in the food industry, and boron-based stabilizers are generally avoided due to their reprotoxic properties.
Innovation Solution
A liquid boron-free enzyme composition comprising 0.5-25% active enzyme protein, 0.05-10% aliphatic 1,2-diols (1,2-pentanediol, 1,2-hexanediol, 1,2-heptanediol, 1,2-octanediol), less than 15% inorganic salts, and 50-98% water, which improves microbial, physical, and enzymatic stability without boron-based stabilizers.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If preservation agents are used to achieve microbial stability, then microbial stability is improved, but harmful factors increase due to biocidal effects and undesirability in food industry
Solution Approach 1:
The patent removes traditional preservation agents from the liquid enzyme formulation, extracting the harmful biocidal components while maintaining microbial stability through alternative means (enzyme formulation and packaging system).
Solution Approach 2:
The patent introduces an intermediary oxygen-barrier packaging system that prevents microbial growth by excluding oxygen, rather than using direct biocidal preservatives. This mediator approach achieves microbial stability without harmful chemical effects.
2Reliability
If boron-based stabilizers are used to maintain enzyme stability, then enzyme stability is improved, but harmful factors increase due to reprotoxic properties
Solution Approach 1:
The patent explicitly excludes boron-based stabilizers from the formulation, removing the harmful reprotoxic substances while maintaining enzyme stability through alternative formulation approaches (pH control, ion composition, packaging).
Solution Approach 2:
The patent uses short-chain fatty acid esters and other safe, biodegradable stabilizing agents that can be easily replaced or degraded, substituting for persistent boron-based stabilizers with safer, temporary alternatives.
3Object-affected harmful factors
If preservative-free formulations are used to eliminate harmful factors, then harmful factors are reduced, but physical stability deteriorates due to formulation complexity
Solution Approach 1:
The patent optimizes specific formulation parameters including pH range (5.0-7.0), water activity, and ion composition ratios to achieve physical stability without preservatives. By carefully controlling these parameters, the formulation maintains stability through natural means.
Solution Approach 2:
The patent uses composite stabilization systems combining multiple components (short-chain fatty acid esters, specific ion combinations, buffer systems) that work synergistically to maintain physical stability in the absence of traditional preservatives.
4Ease of manufacture
If traditional liquid enzyme formulations are used without special packaging, then ease of manufacture is improved, but reliability deteriorates due to microbial contamination
Solution Approach 1:
The patent introduces an oxygen-barrier packaging intermediary that acts as a physical barrier to microbial contamination, allowing simple formulations to achieve high microbial stability through the packaging system rather than complex preservative formulations.
Data Source
AI summary
The invention provides a liquid boron-free enzyme composition, comprising aliphatic 1,2-diols, which exhibit excellent physical and microbial stability.