Boswellic Acids Polysaccharide Composition for Endurance
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Solution Overview
Problem
Current adaptogenic compositions do not effectively enhance physiological endurance and immune response in mammals under physical stress, particularly in addressing chronic restraint stress and hypoxia conditions.
Innovation Solution
A boswellic acids-polysaccharide composition derived from Boswellia serrata, combined with a concentrate of Cocos nucifera liquid endosperm standardized to contain not less than 70% total dissolved solids or an extract of Emblica officinalis fruit standardized to contain 10% w/w 1-O-galloyl-β-D-glucose (β-glucogallin) and not more than 5% w/w gallic acid, is orally administered to increase endurance and immune function.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If conventional adaptogenic compositions are used, then general health support is provided, but physiological endurance and immune response under physical stress are not effectively enhanced
Solution Approach 1:
The patent combines boswellic acids with polysaccharides from Boswellia serrata to create a composite composition that synergistically enhances both immune response and physiological endurance. The composite structure allows the two components to work together, with boswellic acids providing anti-inflammatory effects and polysaccharides supporting immune function, thereby resolving the contradiction between reliable immune enhancement and improved physiological endurance under stress
2Adaptability or versatility
If adaptogens are used to strengthen systems compromised by stress, then non-specific resistance is promoted, but specific clinical conditions are not targeted
Solution Approach 1:
The patent applies local quality by standardizing the composition to contain specific concentrations of boswellic acids (5-20% w/w) and polysaccharides (80-95% w/w), creating regions of high concentration of each active component. This allows the composition to provide both broad adaptogenic effects and targeted therapeutic benefits for specific conditions such as inflammatory disorders and immune deficiencies
3Duration of action of moving object
If boswellic acids-polysaccharide composition is administered, then swimming endurance is enhanced and hypoxia induction is delayed, but composition complexity increases
Solution Approach 1:
The patent segments the complex Boswellia serrata extract into two distinct functional components: boswellic acids (5-20% w/w) for anti-inflammatory and cytoprotective effects, and polysaccharides (80-95% w/w) for immune modulation and endurance enhancement. This segmentation simplifies the composition structure while maintaining the complex therapeutic benefits, making it easier to manufacture and standardize
Data Source
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AI summary
Disclosed is the adaptogenic activity of boswellic acids-polysaccharide compositions derived from Boswellia serrata in combination with either (i) the concentrate of the liquid endosperm of Cocos nucifera or (ii) the extract of Emblica officinalis fruit standardized to contain 10% w/w and above of 1-O-galloyl-β-D-glucose (β-glucogallin).