Topical Botanical Composition for Cortisol and Collagen Skin Aging

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Solution Overview

Problem

There is a need for improved skin care agents that can prevent and reverse the effects of aging on the skin, particularly addressing reduced dermal strength and function due to collagen fragmentation and decreased production in aged skin.

Innovation Solution

Compositions comprising botanical extracts such as Malpighia emarginata, Curcuma longa, Osmanthus fragrans, and Spinacia oleracea are formulated for topical administration, targeting multiple pathways to inhibit cortisol activity, restore collagen homeostasis, and reduce inflammation, thereby reversing, preventing, or slowing age-related skin damage.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If conventional skin care agents are used, then basic skin protection is maintained, but they cannot effectively reverse or prevent age-related skin damage and collagen fragmentation

Engineering Contradiction:

Improveeffectiveness in preventing and reversing skin damageVSAvoidcomplexity of composition formulation

Core Design Contradiction:

ReliabilityVSDevice complexity

Solution Approach 1:

The patent employs composite materials by formulating a skincare composition that integrates multiple botanical extracts (Acerola cherry, Blackberry, Centipeda cunninghamii, Osmanthus fragrans, Spinacia oleracea, and Curcuma longa) with specific functional ingredients. This composite approach allows the composition to simultaneously address multiple aging mechanisms including oxidative stress, inflammation, and collagen degradation, thereby achieving reliable prevention and reversal of skin damage without requiring complex procedural interventions

Inventive Principle:

Principle #40Composite materials

Solution Approach 2:

The skincare composition is designed with multi-functionality to address various aspects of skin aging through a single formulation. The botanical extracts collectively provide antioxidant protection, anti-inflammatory effects, collagen synthesis stimulation, and elastin preservation, enabling the composition to simultaneously prevent and reverse multiple signs of skin aging including wrinkles, loss of elasticity, and age spots

Inventive Principle:

Principle #6Universality (Multi-functionality)

2Adaptability or versatility

If single-ingredient skin care products are used, then the formulation is simple, but they cannot target multiple pathways involved in skin aging and collagen degradation

Engineering Contradiction:

Improveability to target multiple aging pathwaysVSAvoidnumber of ingredients in composition

Core Design Contradiction:

Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The patent applies segmentation by dividing the anti-aging function into multiple specialized botanical extracts, each targeting specific aging pathways. For example, Acerola cherry and Blackberry extracts primarily provide antioxidant protection against oxidative stress, while Centipeda cunninghamii and Osmanthus fragrans focus on anti-inflammatory effects and collagen protection. This segmented approach allows the composition to comprehensively address multiple aging mechanisms through coordinated action of specialized ingredients

Inventive Principle:

Principle #1Segmentation

Solution Approach 2:

The patent merges multiple botanical extracts with complementary functions into a unified skincare composition. By combining antioxidants (Acerola cherry, Blackberry), anti-inflammatory agents (Centipeda cunninghamii, Osmanthus fragrans), and collagen-supporting ingredients (Spinacia oleracea, Curcuma longa), the composition achieves synergistic effects that target multiple aging pathways simultaneously, providing comprehensive protection and reversal of skin damage

Inventive Principle:

Principle #5Merging (Combining)

3Reliability

If topical compositions with multiple botanical extracts are used, then cortisol activity is inhibited and collagen production is restored, but the formulation complexity increases

Engineering Contradiction:

Improveability to inhibit cortisol and restore collagenVSAvoidease of formulation and manufacturing

Core Design Contradiction:

ReliabilityVSEase of manufacture

Solution Approach 1:

The patent applies parameter changes by optimizing the concentration ranges of each botanical extract to achieve effective cortisol inhibition and collagen restoration. The formulation specifies precise concentration parameters for each ingredient (e.g., Acerola cherry extract at 0.1-5%, Blackberry extract at 0.1-5%, Centipeda cunninghamii extract at 0.1-5%) to ensure synergistic effectiveness while maintaining manufacturing feasibility. This parameter optimization allows the complex multi-ingredient composition to be manufactured with standard pharmaceutical processes

Inventive Principle:

Principle #35Parameter changes

Data Source

PatentUS12544329B2Compositions and methods for treating and preventing skin damage

Publication Date: 2026.02.10 ACCESS BUSINESS GROUP INTERNATIONAL LLC

AI summary

Provided herein are compositions and method for treating and preventing skin damage. In particular, provided herein are compositions that reverse, prevent and/or slow age-related skin damage.