Bowel Cleansing Composition with Reduced Day-of-Exam Dosage
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Solution Overview
Problem
Existing bowel cleansing compositions for colonoscopy are inconvenient and pose safety risks due to high dosages, unpleasant flavors, and the need for large volumes to be consumed quickly, especially on the day of the examination.
Innovation Solution
A bowel cleansing composition that is taken in divided doses the day before and on the day of the examination, with a total dosage on the day of the examination limited to 700 mL or less, using a preparation solution and a water-soluble solvent administered separately.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If a large amount of bowel cleanser (1-2 L) is taken within a short period on the day of colonoscopy, then bowel cleansing effectiveness is improved, but safety is worsened due to contradiction with fasting requirements for gastroscopy and sedative anesthesia
Solution Approach 1:
The patent divides the total bowel cleanser dosage into two separate administrations: the first dose is taken the evening before the examination, and the second dose is taken on the morning of the examination. This segmentation allows the patient to complete bowel preparation without consuming large volumes immediately before the procedure, thus avoiding conflict with fasting requirements for gastroscopy and sedative anesthesia while maintaining effective bowel cleansing.
2Reliability
If most of the bowel cleanser dosage is taken on the day of examination, then bowel cleansing effectiveness is improved, but ease of operation is worsened due to difficulty of taking large volumes quickly
Solution Approach 1:
The patent segments the dosage schedule so that a significant portion (approximately half) of the total bowel cleanser volume is administered the evening before the examination, with the remaining half taken on the morning of the examination. This segmentation distributes the burden of taking large volumes over a longer time period, making it significantly easier for patients to comply without feeling overwhelmed by the need to consume 1-2 liters within a short window.
3Reliability
If fasting for 8 hours including water is required for gastroscopy, then safety for gastroscopy is improved, but ease of operation is worsened by contradiction with bowel cleanser administration
Solution Approach 1:
The patent structures the dosing schedule so that the second and final dose of bowel cleanser is completed by early morning on the day of the examination, allowing patients to fulfill both the bowel preparation requirement and the 8-hour fasting requirement for gastroscopy without conflict. This segmentation enables sequential completion of both preparation protocols.
Solution Approach 2:
The patent performs the first bowel cleanser administration in advance (the evening before the examination), completing a significant portion of bowel preparation before the fasting period begins. This preliminary action reduces the burden on the morning of the examination and allows the fasting requirement to be met without compromising bowel preparation quality.
4Reliability
If 3 hours fasting before sedative anesthesia is required, then safety for sedation is improved, but ease of operation is worsened by contradiction with bowel cleanser intake
Solution Approach 1:
The patent segments the bowel cleanser administration so that the final dose is completed well before the 3-hour fasting window required for sedative anesthesia. This ensures that by the time sedation is administered, the patient has not consumed any bowel cleanser or water for the required period, maintaining safety while preserving bowel preparation effectiveness.
Data Source
AI summary
The present invention relates to a bowel cleansing composition and, specifically, to a bowel cleansing composition that reduces the dosage required on the day of examination requiring bowel cleansing, thereby increasing safety.