Brachytherapy Supervision via SPECT-CT Registration

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Solution Overview

Problem

Current brachytherapy treatments lack real-time verification and supervision, leading to potential errors due to patient motion, organ filling changes, and incorrect radiation source positioning, which can result in significant clinical impacts and radiation events caused by human errors.

Innovation Solution

A system incorporating a medical imaging system with SPECT or CT units and a processing unit to acquire and register planning and supervision datasets, enabling real-time monitoring and comparison of planned and actual dose distributions, providing supervision information for accurate radiation source positioning and treatment verification.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If real-time supervision and verification are implemented during brachytherapy treatment, then treatment accuracy and safety are improved, but device complexity and treatment time increase

Engineering Contradiction:
Improvetreatment accuracyVSAvoidsystem complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent implements real-time feedback by continuously monitoring the actual positions of radiation sources and medical guide instruments during brachytherapy treatment using electromagnetic tracking. The system compares actual treatment delivery against the treatment plan and provides immediate feedback to alert operators of any deviations, enabling corrective actions before significant errors occur.

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The patent introduces electromagnetic tracking markers as intermediaries attached to radiation sources and medical guide instruments. These markers serve as mediators that enable indirect tracking and verification of component positions without requiring direct observation or complex imaging during treatment delivery.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Measurement precision

If electromagnetic tracking markers are attached to radiation sources and medical guide instruments, then positioning accuracy is improved, but device complexity and preparation time increase

Engineering Contradiction:
Improvepositioning accuracyVSAvoidinstrument complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent applies electromagnetic tracking markers to radiation sources and medical guide instruments during the planning and preparation phase before treatment delivery. This preliminary action ensures that tracking capability is already in place, allowing for seamless real-time monitoring without adding complexity during the actual treatment execution.

Inventive Principle:
Principle #10Preliminary action

3Productivity

If multiple channels of the afterloader unit are used to deliver treatment simultaneously, then treatment efficiency is improved, but the risk of connection errors and dosimetric deviations increases

Engineering Contradiction:
Improvetreatment efficiencyVSAvoidconnection accuracy
Core Design Contradiction:
ProductivityVSReliability

Solution Approach 1:

The patent implements real-time feedback for each channel of the afterloader unit by tracking the positions of radiation sources and medical guide instruments independently. The system monitors and compares actual treatment delivery against the treatment plan for each channel, providing immediate feedback to identify connection errors or deviations before they result in significant dosimetric errors.

Inventive Principle:
Principle #23Feedback

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables real-time brachytherapy treatment supervision and verification, reducing errors by providing immediate feedback on radiation source positioning and dose distribution deviations, thus ensuring accurate and safe treatment delivery.

Implementation Method 1

The SPECT unit is configured to map gamma photons emitted by the at least one radiation source

Methodology Applied
Scientific EffectGamma photon detection: Absorption (EM radiation)

Implementation Method 2

the medical imaging system includes a single photon emission computed tomography (SPECT) unit and/or a computed tomography (CT) unit

Methodology Applied
Scientific EffectX-ray transmission: X-Ray

Data Source

PatentUS20220288417A1System for supporting a brachytherapy treatment, method for providing a supervision information and computer program product
Publication Date: 2022.09.15 SIEMENS MEDICAL SOLUTIONS USA INC
  • US20220288417A1 patent drawing
  • US20220288417A1 patent drawing
  • US20220288417A1 patent drawing

AI summary

A system for supporting a brachytherapy treatment includes a medical imaging system and a processing unit. The medical imaging system includes a SPECT unit and/or a CT unit. The processing unit is configured to receive a planning dataset, and determine a brachytherapy treatment plan based on the planning dataset. The treatment plan includes a planned dose distribution for a radiation source. The medical imaging system is configured to acquire a supervision dataset that includes an intra-procedural representation of the radiation source that, in an operating state of the system, has been positioned at a treatment site within a treatment region via a medical guide instrument. The processing unit is configured to register the supervision dataset and the planning dataset, determine an actual dose distribution based on the supervision dataset, and provide supervision information based on a comparison between the planned and actual dose distribution.