Brain Atrophy Display Using MRI Registration for Dementia Diagnosis

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Solution Overview

Problem

Doctors face difficulty in determining dementia based on numerical atrophy rates calculated for each brain region, making it challenging to support accurate diagnosis.

Innovation Solution

A medical information display apparatus and program that displays brain atrophy states by dividing MRI images into specific brain areas, calculating atrophy rates, and correlating them with diagnostic test results to support dementia diagnosis.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If atrophy rates are calculated for each brain region using MRI images, then measurement precision of brain atrophy is improved, but ease of operation for doctors in determining dementia deteriorates

Engineering Contradiction:
Improveatrophy rate measurementVSAvoiddementia determination
Core Design Contradiction:
Measurement precisionVSEase of operation

Solution Approach 1:

The patent applies color coding to represent different atrophy rate levels in brain region images. Regions with high atrophy rates are displayed in red, moderate rates in yellow, and low rates in green, enabling doctors to quickly assess dementia risk without analyzing numerical data for each region

Inventive Principle:
Principle #32Color changes

Solution Approach 2:

The patent divides the brain into multiple functional regions and calculates atrophy rates for each segment separately. This segmentation allows precise measurement while the visual aggregation of these segments into color-coded regions maintains ease of interpretation

Inventive Principle:
Principle #1Segmentation

2Measurement precision

If brain images are divided into multiple regions for detailed analysis, then measurement precision of atrophy changes is improved, but device complexity increases

Engineering Contradiction:
Improveregional atrophy analysisVSAvoidimage processing system
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent combines multiple divided brain region images into a single composite image where each region is color-coded according to its atrophy rate. This merging process integrates detailed regional data while presenting a unified, easy-to-interpret visual summary that reduces system complexity

Inventive Principle:
Principle #5Merging (Combining)

3Measurement precision

If numerical atrophy rates are calculated for diagnostic purposes, then measurement precision is improved, but loss of information in visual interpretation increases

Engineering Contradiction:
Improveatrophy rate calculationVSAvoidvisual diagnostic information
Core Design Contradiction:
Measurement precisionVSLoss of information

Solution Approach 1:

The patent encodes numerical atrophy rate information into visual color codes that preserve diagnostic information. The color-coded regional display maintains the precision of numerical calculations while restoring visual interpretability, preventing information loss in the diagnostic process

Inventive Principle:
Principle #32Color changes

Data Source

PatentEP3677180B1Medical information display device and program
Publication Date: 2026.02.25 FUJIFILM CORP
  • EP3677180B1 patent drawingFigure 1
  • EP3677180B1 patent drawingFigure 2
  • EP3677180B1 patent drawingFigure 3~4

AI summary

The present invention provides a medical information display apparatus, a medical information display method, and a medical information display program capable of appropriately displaying an atrophy state of the brain in order to support a doctor's diagnosis of dementia. The medical information display apparatus includes an image acquisition unit that acquires a first brain image which is a brain image of a subject captured at a first time point and a second brain image which is a brain image of the subject captured at a second time point later in time than the first time point, a registration unit that performs registration between the first brain image and the second brain image, an image analysis unit that extracts a first cavity region and a second cavity region from the first brain image and the second brain image, respectively, a display unit, and a display controller that displays, on the display unit, a cavity expansion part included in a first non-cavity region, which is a region other than the first cavity region in the first brain image, and included in the second cavity region in a distinguishable manner from a region other than the cavity expansion part from a result of the registration between the first brain image and the second brain image.