Brain Function Measurement Device with Optical Attenuator Calibration

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Solution Overview

Problem

Existing brain function measurement devices using functional near-infrared spectroscopy face challenges in maintaining consistent signal-to-noise ratios due to variations in optical attenuation caused by hair and adhesion, requiring precise calibration of optical attenuators.

Innovation Solution

A brain function measurement device and method that adjusts the light amounts between light irradiation and detection probes using optical attenuators to level observed light amounts across channels, eliminating the need for calibration by selecting probes with maximum effective incident light and detection efficiency and performing adjacent channel leveling operations.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If optical attenuators are introduced to level noise variance across channels, then measurement precision is improved, but device complexity increases due to the need for calibration of all optical attenuators

Engineering Contradiction:
Improvesignal-to-noise ratio consistencyVSAvoidcalibration operation complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent extracts the calibration operation from the device setup process by using a calibration value stored in memory that was pre-obtained during manufacturing. This eliminates the need for on-site calibration of optical attenuators, reducing device complexity while maintaining measurement precision through the use of pre-determined calibration parameters.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The calibration values for optical attenuators are determined in advance during manufacturing and stored in memory. This preliminary action allows the device to be used immediately without requiring calibration operations at the measurement site, thereby reducing device complexity and setup time while ensuring measurement precision.

Inventive Principle:
Principle #10Preliminary action

2Measurement precision

If calibration operations are performed for all optical attenuators, then measurement precision is improved, but loss of time increases due to the lengthy calibration process

Engineering Contradiction:
Improvesignal-to-noise ratio consistencyVSAvoidcalibration time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

Calibration values are determined during manufacturing and stored in memory before the device is deployed. This preliminary calibration action eliminates the need for time-consuming calibration operations at the measurement site, significantly reducing loss of time while maintaining measurement precision through the use of pre-determined optimal parameters.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent uses a calibration value that represents the optimal attenuation setting, copying this pre-determined value into memory for reuse. This allows the device to replicate the calibrated state without repeating the calibration process, thereby eliminating time loss while maintaining precision.

Inventive Principle:
Principle #26Copying

3Measurement precision

If optical attenuators are used to equalize light amounts across channels, then measurement precision is improved, but ease of operation deteriorates due to the need for precise attenuation control

Engineering Contradiction:
Improvenoise variance equalizationVSAvoidoptical attenuator adjustment
Core Design Contradiction:
Measurement precisionVSEase of operation

Solution Approach 1:

The control unit automatically controls the optical attenuators based on the calibration value stored in memory, eliminating the need for manual adjustment. This self-service operation maintains measurement precision through accurate attenuation control while significantly improving ease of operation, as users simply need to initiate the measurement process without dealing with complex manual adjustments.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The control unit uses the calibration value to automatically adjust optical attenuators, creating a feedback-controlled system that maintains optimal light amounts across channels. This automated feedback mechanism ensures measurement precision while improving ease of operation, as the system self-regulates without requiring user intervention.

Inventive Principle:
Principle #23Feedback

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach allows for noise leveling across channels without calibrating optical attenuators, simplifying device adjustment and maintenance, and enabling statistical comparison of data across different dates and subjects while maintaining a high signal-to-noise ratio within safe light irradiation limits.

Implementation Method 1

functional near-infrared spectroscopy (fNIRS) has been known. Measurement using fNIRS is performed with probes attached to the scalp

Methodology Applied
Scientific EffectNear-infrared spectroscopy: Absorption Spectroscopy

Implementation Method 2

introducing optical attenuators between the respective light sources or detectors and the living body, and controlling the optical transmittance of the optical attenuators

Methodology Applied
Scientific EffectOptical attenuation: Absorption (EM radiation)

Data Source

PatentEP3610796B1Brain function measurement device and method
Publication Date: 2024.09.25 NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE & TECHNOLOGY
  • EP3610796B1 patent drawingFigure 1~2
  • EP3610796B1 patent drawingFigure 3
  • EP3610796B1 patent drawingFigure 4

AI summary

The present invention addresses the problem of providing a brain function measurement device and a brain function measurement method with which it is possible to eliminate or minimize the need for a calibration operation. The problem is solved by a brain function measurement device including: a first light irradiation probe S1 which irradiates the brain of a subject with light; a first light detection probe D1 which is disposed adjacent to the first light irradiation probe S1 and detects light reflected from the brain among the light irradiated from the first light irradiation probe S1; a second light irradiation probe S2 which is disposed adjacent to the first light detection probe D1 and irradiates the brain of the subject with light; a second light detection probe D2 which is disposed adjacent to the second light irradiation probe S2 and detects light reflected by the brain among the light irradiated from the second light irradiation probe S2; and a control unit 3 which adjusts the light amount irradiated by the second light irradiation probe S2 so that the light amount measured with respect to a channel between the first light detection probe D1 and the second light irradiation probe S2 becomes an observation value observed with respect to a channel between the first light irradiation probe S1 and the first light detection probe D1, and which adjusts the light amount detected by the second light detection probe D2 so that the light amount measured with respect to a channel between the second light irradiation probe S2 and the second light detection probe D2 becomes the observation value.