Computer Brain Interface Autocalibration for Positional Drift

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Solution Overview

Problem

Existing CBI devices struggle with maintaining consistent and high-fidelity neural responses due to positional sensitivity and non-linear neural dynamics, particularly in moving individuals, leading to unreliable information transfer.

Innovation Solution

A closed-loop autocalibration method that applies burst sequences of stimulation pulses to afferent sensory neurons, records bioelectric responses, and adjusts stimulation parameters based on derived neural excitability profiles to account for non-linear and dynamic neuronal behavior.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If neurostimulation electrodes are calibrated for a specific relative orientation and distance, then consistent neural response is achieved under those conditions, but the neural response becomes unreliable when electrodes move relative to the stimulation target

Engineering Contradiction:
Improveneural response consistencyVSAvoidposition invariance
Core Design Contradiction:
ReliabilityVSAdaptability or versatility

Solution Approach 1:

The system transitions from static calibration to dynamic recalibration. The calibration process is performed periodically or triggered by detected movements, allowing the system to adapt to changing electrode-neuron relationships. This resolves the contradiction by making the calibration state dynamic rather than fixed, maintaining reliability under varying positions.

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The system uses feedback from neural response monitoring to guide recalibration. By continuously or periodically assessing the neural response and comparing it against expected patterns, the system identifies drift and initiates recalibration only when necessary. This selective feedback mechanism maintains reliability without the overhead of continuous recalibration.

Inventive Principle:
Principle #23Feedback

2Measurement precision

If complex and fine-tuned neurostimulation signals are used for high bandwidth CBI, then information transfer fidelity is improved, but positional sensitivity effects become more severe

Engineering Contradiction:
Improveinformation transfer fidelityVSAvoidpositional sensitivity
Core Design Contradiction:
Measurement precisionVSObject-affected harmful factors

Solution Approach 1:

The system performs preliminary recalibration before significant position changes occur. By monitoring for movement events or time-based triggers and initiating calibration sequences in advance, the system ensures that complex fine-tuned signals are always delivered with accurate calibration parameters, preventing fidelity degradation from positional drift.

Inventive Principle:
Principle #10Preliminary action

3Reliability

If calibration is performed continuously to maintain reliability, then neural response consistency is improved, but device complexity and computational load increase

Engineering Contradiction:
Improveneural response consistencyVSAvoidcalibration system complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

Instead of continuous calibration, the system applies partial calibration at strategically determined intervals or triggered by specific events. This partial action approach maintains sufficient reliability for most operational conditions while significantly reducing computational load and system complexity compared to truly continuous calibration.

Inventive Principle:
Principle #16Partial or excessive action

Data Source

PatentUS12409325B2Closed-loop autocalibration method for a computer brain interface device, computer program and computer brain interface device
Publication Date: 2025.09.09 CEREGATE GMBH
  • US12409325B2 patent drawing
  • US12409325B2 patent drawing
  • US12409325B2 patent drawing

AI summary

A computer brain interface (CBI) device of an individual applies a burst sequence of stimulation pulses to afferent sensory nerve fibers to elicit a bioelectric response via a neurostimulation interface operably connected to or integrated with the CBI device. The neurostimulation interface senses the bioelectric responses of the stimulated afferent sensory nerve fibers. The CBI device derives, based on the sensed bioelectric responses, a neural excitability profile characterizing a non-linear, dynamic excitation behavior of the afferent sensory neurons corresponding to the applied sequence of stimulation pulses. At least one stimulation parameter of the current set of stimulation parameters is adjusted based on the derived excitability profile to obtain an updated set of stimulation parameters.