Brain Landmark Localization Using Probability Maps and Coordinate Alignment

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Solution Overview

Problem

Existing methods for manually localizing brain structure identifiers such as the anterior commissure (AC), posterior commissure (PC), and midsagittal plane (MSP) are time-consuming, subjective, and lack repeatability, with existing automatic solutions being inefficient and lacking robustness.

Innovation Solution

A system utilizing a neural network model to automatically determine region, landmark, and plane identifiers from brain images, constructing a target coordinate system based on these identifiers, and determining landmarks like AC, PC, and MSP with high accuracy.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If manual localization is performed by doctors, then accuracy can be maintained through expert judgment, but the process becomes time-consuming and lacks repeatability

Engineering Contradiction:
Improvelocalization accuracyVSAvoidlocalization time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The patent replaces the manual mechanical localization process with an automated computer-based system that uses image processing algorithms to automatically identify and locate brain identifiers such as AC, PC, and MSP landmarks, eliminating the need for manual doctor intervention while maintaining localization accuracy

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The system enables self-service localization where the computer automatically performs the localization task without requiring expert medical personnel to manually identify landmarks, allowing the system to serve itself in completing the localization process

Inventive Principle:
Principle #25Self-service

2Loss of time

If existing automatic determination solutions are implemented, then time consumption is reduced, but the processing process becomes complicated and robustness deteriorates

Engineering Contradiction:
Improvelocalization timeVSAvoidprocessing complexity
Core Design Contradiction:
Loss of timeVSDevice complexity

Solution Approach 1:

The patent segments the localization task into distinct components: image acquisition, probability map generation for different brain identifiers, and coordinate system construction. Each component is processed independently through dedicated neural network models, simplifying the overall complex process while maintaining automation benefits

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The system employs a universal neural network framework that can handle multiple types of brain identifiers (AC, PC, MSP, and cortical landmarks) simultaneously through a unified probability map generation approach, reducing processing complexity compared to separate specialized algorithms for each identifier type

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Extent of automation

If existing automatic determination solutions are used, then automation is achieved, but efficiency and practical value remain low

Engineering Contradiction:
Improvelocalization automationVSAvoidprocessing efficiency
Core Design Contradiction:
Extent of automationVSProductivity

Solution Approach 1:

The patent changes the operational parameters by using probability map generation as an intermediate representation, allowing the system to efficiently query and extract multiple brain identifier locations from a single processed image, significantly improving productivity compared to sequential detection methods

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The system performs preliminary action by pre-generating comprehensive probability maps that contain information about all brain identifiers before actual localization queries are made. This preliminary processing enables rapid subsequent queries without reprocessing the original image, enhancing overall efficiency

Inventive Principle:
Principle #10Preliminary action

Data Source

PatentUS12608814B2Systems and methods for brain identifier localization
Publication Date: 2026.04.21 WUHAN UNITED IMAGING HEALTHCARE SURGICAL TECH CO LTD
  • US12608814B2 patent drawing
  • US12608814B2 patent drawing
  • US12608814B2 patent drawing

AI summary

Embodiments of the present disclosure provide systems and methods for brain identifier localization. The methods include obtaining an image of a brain; determining region identifier probability map(s) of the brain, landmark identifier probability map(s) of the brain, and plane identifier probability map(s) of the brain based on the image and a neural network model; determining a segmentation result of a cerebral cortex of the brain, landmark identifier(s) of the brain, and plane identifier(s) of the brain, respectively, based on the region identifier probability map(s), the landmark identifier probability map(s), and the plane identifier probability map(s); constructing a target coordinate system based on the landmark identifier(s) and the plane identifier(s); and determining landmark(s) of the cerebral cortex based on the segmentation result of the cerebral cortex, the target coordinate system, and/or the landmark identifier(s).