Brain MRI Projection Image Generation for Micro Bleed Visualization

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Solution Overview

Problem

Current methods for diagnosing dementia, particularly vascular dementia, face challenges in accurately counting micro bleeds (MBs) in three-dimensional MRI images due to overlapping issues, lack of objective criteria, and difficulty in distinguishing MBs from other brain features, leading to underestimation and overlapping of lesions in projection images.

Innovation Solution

An image processing apparatus that generates projection images of the brain by performing a minimum Intensity Projection (mIP) method within a range limited by the brain's shape, allowing for clearer visualization and identification of MBs or calcification sites without overlapping, and outputs these images with the brain surface for enhanced diagnostic clarity.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If conventional projection methods are used to visualize MBs in three-dimensional MRI images, then the images can be generated quickly, but the MBs overlap and cannot be accurately counted or distinguished from other brain features

Engineering Contradiction:
Improveaccuracy of MB countingVSAvoidcomplexity of image processing method
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent segments the three-dimensional brain image data into multiple two-dimensional slice images along the projection direction. By processing and displaying individual slices separately, the method prevents overlapping of micro bleeds that occurs in conventional projection methods, enabling accurate counting and identification of MBs while maintaining relatively simple processing procedures.

Inventive Principle:
Principle #1Segmentation

2Area of stationary object

If the entire brain volume is projected to visualize all MBs, then comprehensive coverage is achieved, but MBs overlap and diagnostic clarity is reduced

Engineering Contradiction:
Improvecoverage area of projection imageVSAvoiddiagnostic accuracy
Core Design Contradiction:
Area of stationary objectVSReliability

Solution Approach 1:

The patent transitions from three-dimensional volume projection to two-dimensional slice display. By presenting multiple 2D slices along the projection direction instead of a single 3D projection, the method maintains comprehensive coverage of the entire brain volume while eliminating the overlapping problem, thereby improving diagnostic accuracy and reliability.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

3Productivity

If conventional projection methods are used, then processing speed is maintained, but objective criteria for MB identification are lacking leading to underestimation

Engineering Contradiction:
Improveimage processing speedVSAvoidobjectivity of MB detection
Core Design Contradiction:
ProductivityVSMeasurement precision

Solution Approach 1:

The segmentation of 3D volume data into 2D slices provides clear visual separation of micro bleeds, enabling objective identification and counting. Each slice can be independently analyzed with established criteria, eliminating the subjectivity and underestimation problems associated with conventional projection methods while maintaining efficient processing speeds.

Inventive Principle:
Principle #1Segmentation

Data Source

PatentUS11903745B2Image processing apparatus
Publication Date: 2024.02.20 CANON MEDICAL SYST CORP
  • US11903745B2 patent drawing
  • US11903745B2 patent drawing
  • US11903745B2 patent drawing

AI summary

An image processing apparatus according to an embodiment includes processing circuitry. The processing circuitry is configured to obtain three-dimensional image data of a brain acquired by performing a magnetic resonance imaging process. The processing circuitry is configured to generate a projection image rendering a micro bleed or calcification occurring in the brain by performing a projecting process on the three-dimensional image data in a range limited on the basis of a shape of the brain. The processing circuitry is configured to output the projection image.