Aerodynamic Breath Droplet Sorting System

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Solution Overview

Problem

Existing filter-based techniques for sampling human breath are inadequate as they introduce additional pressure, altering the user's breathing pattern and potentially contaminating the sample with saliva droplets, which can dilute the metabolomic content.

Innovation Solution

A system that uses a mouthpiece with a flow path featuring bends and adjustable dimensions to sort aerosol droplets based on mass-size, directing larger droplets to a saliva reservoir while allowing smaller ones to pass through, utilizing a condenser tube with a cooling mechanism for collection and minimizing pressure resistance.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If a physical membrane-based filter is used to catch larger saliva droplets, then saliva droplet filtration is improved, but additional pressure is introduced into the flow path

Engineering Contradiction:
Improvesaliva droplet filtrationVSAvoidpressure in flow path
Core Design Contradiction:
ReliabilityVSStress or pressure

Solution Approach 1:

The patent removes the filter element from the flow path entirely, extracting the harmful filtering function and replacing it with a filterless design that uses aerodynamic sorting to separate droplets based on their mass and trajectory in response to flow direction changes

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent replaces the mechanical filter-based separation system with an aerodynamic system that uses flow direction changes and inertial effects to sort droplets by mass-size, eliminating the need for physical filtration membranes

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Reliability

If a filter is placed in the flow path to remove saliva droplets, then saliva droplet removal is improved, but the user's natural breathing pattern is altered

Engineering Contradiction:
Improvesaliva droplet removalVSAvoidbreathing pattern
Core Design Contradiction:
ReliabilityVSEase of operation

Solution Approach 1:

The filter is completely removed from the flow path, eliminating the source of breathing pattern disruption while maintaining saliva droplet removal capability through aerodynamic sorting mechanisms

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent introduces flow direction changes and aerodynamic forces as intermediary mechanisms that indirectly separate saliva droplets without requiring direct physical contact with filtering surfaces that would impede breathing

Inventive Principle:
Principle #24Intermediary (Mediator)

3Ease of operation

If saliva droplets are not filtered out, then breathing pattern remains natural, but sample contamination and dilution occur

Engineering Contradiction:
Improvebreathing patternVSAvoidsample purity
Core Design Contradiction:
Ease of operationVSReliability

Solution Approach 1:

The patent replaces mechanical filtration with aerodynamic sorting using flow direction changes that exploit differences in droplet mass and inertia to separate saliva droplets from the breath sample, maintaining natural breathing while ensuring sample purity

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent changes the separation mechanism from physical filtration to aerodynamic sorting based on mass-size parameters, using flow direction changes to differentiate between saliva droplets and smaller aerosol particles containing metabolomic information

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Effectively filters out saliva droplets without altering the breathing pattern, preserving the metabolomic content by ensuring minimal pressure resistance and efficient condensation, allowing for accurate sorting and collection of smaller droplets containing valuable metabolites.

Implementation Method 1

aerosol droplets in the flow having different mass-sizes to change direction at different rates because of differences in momentum for different droplet masses

Methodology Applied
Scientific EffectMomentum: Conservation of Momentum

Implementation Method 2

differences in air-flow-related frictional forces for different droplet sizes

Methodology Applied
Scientific EffectFriction: Friction

Implementation Method 3

the condenser tube includes a cooling mechanism that cools the condenser tube to facilitate condensing aerosol droplets to sides of the condenser tube for subsequent collection

Methodology Applied
Scientific EffectCondensation: Condensation

Data Source

PatentUS11813050B2Selectively sorting aerosol droplets in exhaled human breath based on a mass-size parameter
Publication Date: 2023.11.14 RGT UNIV OF CALIFORNIA
  • US11813050B2 patent drawing
  • US11813050B2 patent drawing
  • US11813050B2 patent drawing

AI summary

A selective-sorting system for aerosol droplets in human breath includes a mouthpiece to receive a flow of human breath, and a flow path coupled to the mouthpiece. This flow path includes one or more bends that cause the flow of human breath to change direction, which causes aerosol droplets in the flow having different mass-sizes to change direction at different rates. Moreover, the flow path is shaped so that droplets that change direction at different rates are directed to different destinations. The system also includes a collection path, which is coupled to the flow path so that aerosol droplets meeting a specific mass-size criterion are directed into the collection path. A condenser tube is located in the collection path, wherein the condenser tube includes a cooling mechanism that cools the condenser tube to facilitate condensing aerosol droplets to sides of the condenser tube for subsequent collection.