Breath Gas Sensor Array Layout for Early VOC Detection

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Solution Overview

Problem

Existing methods for detecting diseases through volatile organic compounds in gaseous samples are not efficient or accurate, particularly in providing early detection of disease states.

Innovation Solution

A gas measurement device with a housing containing a fluid ingress and egress port, a circuit board with gas sensors, and a configuration that allows for efficient gas flow and electrical communication, utilizing graphene varactors to detect specific chemical compounds in breath samples.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If traditional disease detection methods are used, then detection capability is provided, but detection accuracy and efficiency are insufficient for early disease detection

Engineering Contradiction:
Improvedetection accuracyVSAvoiddetection reliability
Core Design Contradiction:
Measurement precisionVSReliability

Solution Approach 1:

The device segments the detection task by using multiple gas sensors with different sensitivities arranged in an array, each sensor detecting different aspects of VOC profiles. This segmentation allows for more comprehensive and accurate disease detection compared to single-sensor systems

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent introduces graphene varactors as intermediary sensing elements that convert chemical interactions with VOCs into measurable electrical signals. These varactors act as mediators between the gas molecules and the measurement system, enabling highly sensitive detection of disease-related compounds

Inventive Principle:
Principle #24Intermediary (Mediator)

2Measurement precision

If multiple gas sensors are used to improve detection accuracy, then measurement precision improves, but device complexity increases

Engineering Contradiction:
Improvedetection accuracyVSAvoidsensor array complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent merges multiple gas sensors onto a single circuit board within a unified housing structure. The sensors are integrated with shared electrical connections and signal processing circuitry, reducing overall system complexity while maintaining high detection accuracy through multi-sensor arrays

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The circuit board serves multiple functions: it provides mechanical support for the sensor array, electrical connections for all sensors, signal processing capabilities, and data output interfaces. This multi-functionality reduces the need for separate components and simplifies the overall device architecture

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Volume of moving object

If a compact device design is implemented, then device portability improves, but gas flow path efficiency may be compromised

Engineering Contradiction:
Improvedevice sizeVSAvoidgas analysis efficiency
Core Design Contradiction:
Volume of moving objectVSProductivity

Solution Approach 1:

The patent optimizes the gas flow path by utilizing three-dimensional space within the compact housing. The flow path winds through the interior volume in multiple dimensions, ensuring efficient gas distribution across all sensors without requiring a large device footprint. This dimensional optimization maintains analysis efficiency while achieving compact form factor

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The device provides a compact and efficient design for detecting health status and disease states by analyzing gas samples, offering improved accuracy and early disease detection.

Implementation Method 1

Some disease states result in the production of specific chemical compounds. In some cases, volatile organic compounds (VOCs) released into a gaseous sample of a patient can be hallmarks of certain diseases. The detection of these compounds or differential sensing of the same can allow for the early detection of particular disease states.

Methodology Applied
Scientific EffectVolatile organic compound detection: Absorption (physical)

Data Source

PatentUS12517100B2Fluid analysis system
Publication Date: 2026.01.06 REGENTS OF THE UNIVERSITY OF MINNESOTA
  • US12517100B2 patent drawing
  • US12517100B2 patent drawing
  • US12517100B2 patent drawing

AI summary

Embodiments herein relate to breath analysis system. In an embodiment, a gas measurement device is included having a housing defining an interior volume. The housing can include a fluid ingress port, a fluid egress port, a bottom wall, and a circuit board disposed within the interior volume. The circuit board can include a first side and a second side, where the first side of the circuit board faces inward toward the interior volume. The circuit board can include a plurality of gas sensors disposed on the first side of the circuit board and a plurality of conductive pads disposed on the second side of the circuit board, wherein a plurality of electrical contacts contact the conductive pads when the circuit board is seated within the housing. Other embodiments are also included herein.