Bromochloromethane Preparation with Catalytic Phase Separation

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Solution Overview

Problem

Existing processes for preparing bromochloromethane are inefficient, require expensive starting materials, generate harmful waste streams, and have insufficient yields, making them unsuitable for economical industrial applications.

Innovation Solution

A process involving the reaction of dichloromethane and dibromomethane with specific catalysts, followed by the addition of alcohol or water to form a monophasic or biphasic mixture, which is then separated to obtain high-purity bromochloromethane through distillation, allowing for continuous or discontinuous separation methods.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If dichloromethane and dibromomethane are reacted in the presence of aluminum trichloride, then bromochloromethane is obtained, but the yield is only 76% of theory and the process requires discontinuous extractive aqueous work-up and subsequent discontinuous fractional distillation

Engineering Contradiction:
Improveyield of bromochloromethaneVSAvoidprocess complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The patent changes the catalyst from aluminum trichloride to a combination of aluminum tribromide and iron(III) chloride, which fundamentally alters the reaction parameters and outcome. This catalyst change increases the yield from 76% to over 90% and enables continuous process operation, resolving both the productivity and complexity contradictions

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent implements continuous reaction and continuous separation processes, replacing the discontinuous batch operations with continuous flow chemistry. The reaction mixture is continuously fed into the reactor, and the product is continuously separated via distillation, eliminating idle times and improving overall productivity while simplifying process control

Inventive Principle:
Principle #20Continuity of useful action

2Ease of manufacture

If fluorine-containing haloalkanes are used as starting materials, then bromochloromethane can be prepared, but the starting materials are very expensive and waste streams containing fluorine are formed

Engineering Contradiction:
Improveavailability of starting materialsVSAvoidfluorine waste streams
Core Design Contradiction:
Ease of manufactureVSObject-generated harmful factors

Solution Approach 1:

The patent replaces expensive fluorine-containing haloalkanes with inexpensive, readily available dichloromethane and dibromomethane as starting materials. These common solvents can be obtained from standard chemical suppliers without special handling requirements, dramatically reducing material costs and eliminating fluorine waste stream generation

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

Solution Approach 2:

The patent converts the traditionally harmful halogen exchange reaction into a beneficial process by using catalysts that promote selective bromine-chlorine exchange without generating harmful fluorine waste. The reaction conditions are optimized to maximize product yield while minimizing byproduct formation, turning a potentially polluting process into an environmentally friendly manufacturing method

Inventive Principle:
Principle #22Blessing in disguise (Convert harm into benefit)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The process achieves high yields of bromochloromethane, up to 95-99% of theoretical yield, with reduced waste and energy-efficient separation, suitable for industrial applications.

Implementation Method 1

dichloromethane and dibromomethane is reacted with at least one catalyst selected from the group comprising aluminum trichloride, aluminum tribromide, iron(II) chloride, iron(III) chloride

Methodology Applied
Scientific EffectCatalysis: Catalysis

Implementation Method 2

water and optionally at least one alcohol is added to the first crude mixture obtained in step a), resulting in the formation of a biphasic second crude mixture, which comprises an organic phase and an aqueous phase

Methodology Applied
Scientific EffectPhase separation: Two-Phase Flow

Implementation Method 3

the components dibromomethane, dichloromethane and bromochloromethane are separated from one another, preferably by distillation

Methodology Applied
Scientific EffectDistillation: Distillation

Data Source

PatentUS12565461B2Process for preparing bromochloromethane
Publication Date: 2026.03.03 SALTIGO GMBH

AI summary

The invention relates to an improved process for preparing bromochloromethane by reacting dichloromethane and dibromomethane in the presence of catalysts.