Bromoxynil Formulation Cold Stability via Co-Solvents

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Solution Overview

Problem

Current bromoxynil herbicide formulations face challenges with stability, high cost, and flammability issues due to low solubility and high solvent requirements, limiting their concentration and practical application.

Innovation Solution

Development of highly loaded bromoxynil formulations up to 400 g/L using a combination of low flammability solvents and emulsifiers, ensuring in-can and cold stability, and reducing the need for costly solvents and raw materials.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If bromoxynil is formulated in EC formulations with traditional solvents, then bromoxynil can be delivered at effective rates, but the formulations are prone to form crystals at low temperatures and have limited stability

Engineering Contradiction:
Improvecold stabilityVSAvoiddilution stability
Core Design Contradiction:
ReliabilityVSStability of the object's composition

Solution Approach 1:

The patent changes the chemical parameters of the solvent system by introducing specific co-solvents (N-methyl-2-pyrrolidone, diethylene glycol monobutyl ether) in controlled amounts to modify the solubility characteristics of bromoxynil and prevent crystallization at low temperatures while maintaining dilution stability

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent creates a composite solvent system combining multiple solvents and co-solvents with different properties (Solvesso 150, acetophenone, N-methyl-2-pyrrolidone, diethylene glycol monobutyl ether) to achieve both cold stability and dilution stability that cannot be obtained with single solvents

Inventive Principle:
Principle #40Composite materials

2Productivity

If bromoxynil concentration in EC formulations is increased to reduce application volume, then productivity improves, but the formulations become less stable and more prone to crystallization

Engineering Contradiction:
Improveapplication efficiencyVSAvoidformulation stability
Core Design Contradiction:
ProductivityVSReliability

Solution Approach 1:

The patent modifies the formulation parameters by incorporating specific co-solvents in optimized concentrations (0-50 g/L N-methyl-2-pyrrolidone, 0-20 g/L diethylene glycol monobutyl ether) to enable higher bromoxynil loadings while preventing crystallization and maintaining stability

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The co-solvents act as intermediary substances that mediate between the poorly water-soluble bromoxynil and the aqueous environment, enabling higher concentrations to be maintained in stable solution without premature crystallization

Inventive Principle:
Principle #24Intermediary (Mediator)

3Stability of the object's composition

If traditional EC formulations are used with high solvent content, then bromoxynil solubility is improved, but the cost of raw materials and logistics increase

Engineering Contradiction:
ImprovesolubilityVSAvoidsolvent volume
Core Design Contradiction:
Stability of the object's compositionVSQuantity of substance

Solution Approach 1:

The patent changes the solvent system parameters by introducing high-efficiency co-solvents that significantly improve bromoxynil solubility at low concentrations (0-50 g/L N-methyl-2-pyrrolidone), reducing the overall solvent volume required compared to traditional formulations

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent applies local quality enhancement by using small amounts of highly effective co-solvents in specific regions of the formulation (0-20 g/L diethylene glycol monobutyl ether) to achieve disproportionate improvements in solubility and stability, minimizing total solvent requirements

Inventive Principle:
Principle #3Local quality

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The new formulations provide stable and cost-effective solutions with improved safety and efficiency, allowing for higher bromoxynil concentrations without stability or flammability issues, enhancing weed control efficacy and reducing logistical challenges.

Implementation Method 1

bromoxynil is often formulated in emulsifiable concentrate (EC) formulations

Methodology Applied
Scientific EffectEmulsion: Emulsion

Implementation Method 2

due to the low water solubility of these esters

Methodology Applied
Scientific EffectSolubility: Solvation

Data Source

PatentUS20240349719A1Highly loaded bromoxynil formulations
Publication Date: 2024.10.24 ADAMA AUSTRALIA PTY LTD

AI summary

A highly loaded bromoxynil herbicidal formulation including two emulsifiers and at least one suitable solvent is provided, in which the formulation has low flammability and cold stability. The formulation of the may include one or more other active ingredients.