Bronchial Occlusion for COPD Bypass Activation

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Solution Overview

Problem

Current airway bypass methods for treating chronic obstructive pulmonary disease (COPD) often fail to effectively guide stagnant air from lesion parts to airway bypasses due to non-functioning bypasses in the vicinity of the lesion, leading to inadequate air evacuation.

Innovation Solution

The method involves occluding at least one bronchial tube or emphysema to raise carbon dioxide partial pressure and compress surrounding tissues, facilitating the formation and function of bypasses, and then releasing the occlusion to ensure air is directed through the airway bypass, potentially using a plugging element or expansion body to achieve this.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If a vent hole is formed in the patient's chest to allow air escape, then air evacuation from lung parenchyma is improved, but the bypass function in the vicinity of the lesion part may not be activated

Engineering Contradiction:
Improveair evacuation efficiencyVSAvoidbypass function reliability
Core Design Contradiction:
ProductivityVSReliability

Solution Approach 1:

The patent applies preliminary action by occluding the bronchial tube before allowing air escape through the vent hole. This occlusion creates the necessary conditions (carbon dioxide accumulation and tissue compression) that activate the bypass function in advance, ensuring the bypass is functional when air evacuation begins

Inventive Principle:
Principle #10Preliminary action

2Reliability

If the bronchial tube is occluded to raise carbon dioxide partial pressure and compress tissues, then bypass formation is facilitated, but the lesion part is burdened during the occlusion period

Engineering Contradiction:
Improvebypass formation reliabilityVSAvoidlesion part burden
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent applies periodic action by temporarily occluding the bronchial tube for a specific duration to facilitate bypass formation, then releasing the occlusion. The occlusion is maintained only long enough to achieve bypass formation (indicated by air leakage), after which it is removed to eliminate the burden on the lesion part

Inventive Principle:
Principle #19Periodic action

Solution Approach 2:

The patent uses feedback by monitoring whether air leakage occurs through the bypass to determine when bypass formation is complete. This feedback mechanism allows the treatment to be adjusted - the occlusion is maintained only as long as necessary to achieve the therapeutic effect, then released to avoid prolonged burden on the lesion

Inventive Principle:
Principle #23Feedback

3Reliability

If a plugging element is left indwelling to maintain occlusion, then bypass function is ensured, but continuous treatment instrument connection is required

Engineering Contradiction:
Improvebypass function maintenanceVSAvoidtreatment instrument connection
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent applies self-service by using the patient's own physiological responses (air leakage through the bypass) to indicate successful bypass formation. Once the bypass is formed and functioning, no continuous external instrumentation is needed - the system self-verifies its functionality through the natural air leakage phenomenon

Inventive Principle:
Principle #25Self-service

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach enhances the airway bypass effect by ensuring air from the lesion part is securely sent to the airway bypass, reducing patient burden by eliminating the need for continuous treatment instrument connection and avoiding prolonged occlusion of the lesion.

Implementation Method 1

This makes it possible to raise the carbon dioxide partial pressure in that region inclusive of the emphysema which is governed by the bronchial tube

Methodology Applied
Scientific EffectCarbon dioxide partial pressure increase: Pressure Increase

Implementation Method 2

compress the tissues in the periphery of the lesion part

Methodology Applied
Scientific EffectTissue compression: Compression

Data Source

PatentUS10058332B2Method for treatment of chronic obstructive pulmonary disease
Publication Date: 2018.08.28 TERUMO KK
  • US10058332B2 patent drawing
  • US10058332B2 patent drawing
  • US10058332B2 patent drawing

AI summary

A method for treatment of chronic obstructive pulmonary disease includes occluding at least one of a bronchial tube and emphysema, and deciding whether or not a bypass has been formed by the occlusion.