2,3-Butanediol Purification via pH Adjustment and Membrane Filtration
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Solution Overview
Problem
Current methods for purifying 2,3-butanediol fermentation liquids using nanofiltration membrane treatment followed by distillation still result in significant coloration of the product, which complicates the purification process and reduces the yield.
Innovation Solution
A method involving nanofiltration membrane treatment and ion-exchange treatment of the 2,3-butanediol culture liquid, followed by the addition of an alkaline substance and distillation, effectively removes impurities and prevents coloration, resulting in highly pure and colorless 2,3-butanediol.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Manufacturing precision
If nanofiltration membrane treatment followed by distillation is used to purify 2,3-butanediol fermentation liquid, then high purity 2,3-butanediol can be obtained, but remarkable coloration of the product occurs
Solution Approach 1:
The patent applies preliminary action by adjusting the pH of the fermentation liquid to 2.0 or lower before distillation. This pre-treatment step prevents coloration from occurring during the subsequent distillation process by suppressing the formation of colored impurities through acid-catalyzed reactions, while still allowing high-purity 2,3-butanediol to be obtained through the distillation process.
Solution Approach 2:
The patent changes the pH parameter of the fermentation liquid to 2.0 or lower, which fundamentally alters the chemical environment to prevent coloration. By controlling this critical parameter before distillation, the process achieves both high purity and colorless product, resolving the contradiction between purification effectiveness and product discoloration.
2Manufacturing precision
If multiple purification steps including nanofiltration and distillation are applied, then purity of 2,3-butanediol is improved, but the process complexity increases
Solution Approach 1:
By adjusting pH to 2.0 or lower as a preliminary step before distillation, the patent simplifies the overall process. This pre-treatment prevents coloration formation, eliminating the need for additional color removal steps and reducing process complexity while maintaining high purity through the essential nanofiltration and distillation operations.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This method significantly reduces the degree of pigmentation and improves the purity of 2,3-butanediol, achieving higher distillation yields and producing a product with minimal coloration, as demonstrated by the examples provided.
Implementation Method 1
subjecting a 2,3-butanediol culture liquid produced by microbial fermentation to nanofiltration membrane treatment
Implementation Method 2
subjecting a 2,3-butanediol culture liquid produced by microbial fermentation to nanofiltration membrane treatment and ion-exchange treatment
Implementation Method 3
adding an alkaline substance and performing distillation
Implementation Method 4
performing distillation
Data Source
AI summary
A method of producing 2,3-butanediol includes subjecting a 2,3-butanediol culture liquid produced by microbial fermentation to nanofiltration membrane treatment and ion-exchange treatment (Step A), and then adding an alkaline substance and performing distillation (Step B).