C-Arm Angiography System for Selective Perfusion Analysis
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Solution Overview
Problem
Current imaging methods, such as CT and MRT, are limited in their ability to provide detailed perfusion information of specific tissue regions due to the inability to perform selective arterial contrast agent injections within the imaging device, requiring cumbersome patient transportation and restricting the number of vessels that can be examined.
Innovation Solution
A method involving the generation of functional data sets by recording and analyzing image data sets from selective or superselective contrast agent injections into multiple arteries supplying the same body region, using a C-arm x-ray device to capture images before and after injections, allowing for pixel-based calculation of perfusion parameters and combining these data sets to provide comprehensive perfusion information.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If selective arterial contrast agent injection is performed using MRT or CT, then perfusion information can be obtained, but patient transportation between catheter laboratory and imaging room is required which restricts the number of vessels that can be examined
Solution Approach 1:
The patent combines the catheter laboratory and imaging device into a single integrated system. The C-arm angiography device allows selective arterial contrast agent injection and imaging to be performed in the same location, eliminating the need for patient transportation between facilities. This merging enables examination of multiple vessels sequentially without time loss.
Solution Approach 2:
The C-arm device serves multiple functions: it can perform both catheter-based selective arterial injections and imaging diagnostics in one system. This multi-functionality allows the same device to handle both interventional and diagnostic tasks, replacing the need for separate catheter laboratory and imaging room operations.
2Loss of information
If multiple selective arterial injections are performed to examine different vessels, then comprehensive perfusion data can be obtained, but patient repositioning is required which increases procedure complexity
Solution Approach 1:
The integrated C-arm system allows multiple selective arterial injections into different vessels to be performed sequentially in the same position. The device combines catheter access and imaging capabilities, enabling comprehensive perfusion data collection from multiple arteries without requiring patient repositioning or moving between facilities.
3Productivity
If contrast agent is injected into peripheral veins for bolus tracking, then overall tissue perfusion can be measured, but selective arterial injection for detailed vessel analysis is not possible
Solution Approach 1:
The system enables segmentation of perfusion analysis by allowing selective injection into specific arteries. Instead of only peripheral vein injection that provides overall tissue perfusion, the C-arm system with catheter access allows contrast agent to be injected into individual arteries, enabling vessel-specific perfusion measurement and detailed anatomical analysis.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Enables more informative and precise perfusion analysis of defined structures like the brain and liver, allowing for improved therapeutic planning and evaluation by capturing perfusion parameters such as blood volume and flow without the need for patient repositioning, thereby enhancing the accuracy and efficiency of treatments like embolization.
Implementation Method 1
supplying a first and a second image data set, each comprising at least two images of a perfused region
Implementation Method 2
injection of contrast agent into a first and a second artery supplying the region; generating a first and a second functional data set by pixel-based calculation
Data Source
AI summary
A method and apparatus for generating at least one functional data set of a perfused region of the human or animal body are proposed. A first image data set is supplied comprising at least two images of the perfused region recorded at different times before and after an injection of contrast agent into a first artery supplying the region. A second image data set is supplied comprising at least two images of the perfused region recorded at different times before and after an injection of contrast agent into a second artery supplying the region. A first functional data set is generated by pixel-based calculation of at least one perfusion parameter from the first image data set. A second functional data set is generated by pixel-based calculation of at least one perfusion parameter from the second image data set.