C-Glycoside and Ascorbic Acid Synergy for Procollagen Synthesis

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Solution Overview

Problem

Current cosmetic and dermatological solutions fail to effectively address skin aging and collagen degradation, particularly due to environmental factors like UV exposure, leading to wrinkles, loss of elasticity, and skin thinning.

Innovation Solution

A synergistic combination of ascorbic acid with C-glycoside derivatives such as C-β-D-xylopyranoside-2-hydroxy-propane and C-α-D-xylopyranoside-2-hydroxy-propane is used to stimulate collagen synthesis, preventing and treating signs of aging by enhancing procollagen production.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If ascorbic acid and C-glycoside derivatives are used separately, then some collagen stimulation effect is achieved, but the effect is insufficient to effectively counteract skin aging signs

Engineering Contradiction:
Improveeffectiveness of collagen synthesis stimulationVSAvoidprocollagen production rate
Core Design Contradiction:
ReliabilityVSProductivity

Solution Approach 1:

The patent combines ascorbic acid and C-glycoside derivatives into a single cosmetic composition, merging their individual collagen-stimulating effects into a synergistic combination that produces greater procollagen synthesis than either component alone, effectively resolving the insufficiency of separate applications

Inventive Principle:
Principle #5Merging (Combining)

2Object-affected harmful factors

If environmental protection measures are taken, then skin damage from UV exposure is reduced, but existing signs of aging and collagen degradation cannot be reversed

Engineering Contradiction:
ImproveUV-induced skin damageVSAvoidskin elasticity and collagen integrity
Core Design Contradiction:
Object-affected harmful factorsVSStrength

Solution Approach 1:

The composition applies ascorbic acid and C-glycoside derivatives proactively to stimulate procollagen synthesis before significant aging damage occurs, and to repair existing collagen degradation, addressing both prevention and reversal of aging signs simultaneously

Inventive Principle:
Principle #10Preliminary action

Data Source

PatentEP2043594B1Cosmetic use of a c-glycoside derivative in combination with ascorbic acid
Publication Date: 2017.03.15 LOREAL SA
  • EP2043594B1 patent drawing
  • EP2043594B1 patent drawing
  • EP2043594B1 patent drawing

AI summary

The present invention relates to a cosmetic use of a synergistic combination of at least one C-glycoside derivative with at least ascorbic acid, or one of its derivatives or analogues, for preventively or curatively treating the signs of ageing of body or facial skin, irrespective of whether they are chronobiological or photoinduced.