C-Section Human Milk Fortifier for Nutrient Restoration
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Solution Overview
Problem
Children born via caesarean section are at an increased risk of health issues due to differences in nutrient concentrations in human breast milk compared to those born vaginally, particularly in Human Milk Oligosaccharides (HMOs), vitamins, fatty acids, and minerals, leading to suboptimal growth and development.
Innovation Solution
A pediatric supplement or human milk fortifier composition is developed to address this by including specific nutrients such as ALA, DHA, EPA, 2′FL, LNnT, vitamin A, thiamine, thiamine monophosphate, vitamin B2, vitamin B6, vitamin B9, calcium, and phosphorus, tailored to restore nutrient levels comparable to vaginal delivery, promoting optimal health and development.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If a child is born via caesarean section, then the delivery process is faster and safer for the mother, but the nutrient concentration in human breast milk is reduced, leading to suboptimal growth and development
Solution Approach 1:
The patent introduces a nutritional supplement as an intermediary substance that compensates for the reduced nutrient concentration in breast milk from C-section deliveries. The supplement contains specific nutrients (HMOs, vitamins, fatty acids, minerals) that make up the deficiency, allowing the child to receive adequate nutrition despite the altered breast milk composition from surgical delivery.
Solution Approach 2:
The patent addresses the parameter change in nutrient concentration by modifying the nutritional intake parameters through supplementation. The supplement provides specific amounts of nutrients (e.g., HMOs, vitamin A, DHA) that adjust the total nutrient intake to match the levels achieved through vaginal delivery, thereby compensating for the reduced concentration in C-section breast milk.
2Reliability
If the concentration of nutrients in human breast milk is increased to match vaginal delivery levels, then child health and development are optimized, but the complexity of formulating such a supplement increases
Solution Approach 1:
The patent segments the complex nutritional requirements into distinct nutrient categories (HMOs, vitamins, fatty acids, minerals) and addresses each separately in the supplement formulation. This segmentation allows for targeted provision of specific nutrients that are deficient in C-section breast milk, making the complex formulation task more manageable and systematic.
Solution Approach 2:
The patent creates a composite nutritional supplement that combines multiple nutrients (HMOs, vitamin A, DHA, other fatty acids, vitamins B1-B12, minerals) in a single formulation. This composite approach integrates the various nutrient requirements into one product that collectively restores the nutrient profile of vaginal delivery breast milk, simplifying the delivery mechanism while maintaining comprehensive nutritional support.
Data Source
AI summary
A paediatric supplement or human milk fortifier composition comprising at least one nutrients selected in the list consisting of: ALA, DHA, EPA, 2FL, LNnT, vitamin A, thiamine, thiamine monophosphate, vitamin B2, vitamin B6, vitamin B9, calcium and phosphorus, GD3, GM3. Said paediatric supplement or human milk fortifier composition is tailored or adapted for a child born via C-section who is breast fed and/or to fortify the breast milk of a woman who has given birth via C-section. Said paediatric supplement or human milk fortifier composition is beneficial to provide adequate nutrition to a child born via C-section and promote associated health benefits.