C60 Ketone Ester Composition for Antioxidant and Energy Boost

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Solution Overview

Problem

Existing fullerene compositions do not effectively address both reducing free radicals and improving energy production simultaneously.

Innovation Solution

Substituting fullerene molecules, preferably C60, with beta-hydroxybutyrate (BHB) groups to enhance antioxidant and energy-boosting properties, optionally combined with carboxylic acids like C8 caprylic and C10 capric acids, and using a medium chain triglyceride carrier with a plant-based emulsifier like lecithin.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Object-affected harmful factors

If fullerene is used alone, then antioxidant activity is improved, but energy production enhancement is not achieved

Engineering Contradiction:
Improvefree radical neutralizationVSAvoidenergy production
Core Design Contradiction:
Object-affected harmful factorsVSUse of energy by moving object

Solution Approach 1:

The patent combines fullerene (C60) with ketone esters (beta-hydroxybutyrate and acetoacetate) into a single nutraceutical composition. The fullerene provides antioxidant activity by neutralizing free radicals, while the ketone esters provide energy production through mitochondrial metabolism. This merging of two distinct functional components into one composition simultaneously achieves both free radical neutralization and energy production enhancement without requiring separate supplements.

Inventive Principle:
Principle #5Merging (Combining)

2Use of energy by moving object

If ketone esters are used alone, then energy production is improved, but antioxidant activity is not achieved

Engineering Contradiction:
Improveenergy productionVSAvoidfree radical neutralization
Core Design Contradiction:
Use of energy by moving objectVSObject-affected harmful factors

Solution Approach 1:

The patent integrates ketone esters (which enhance energy production via mitochondrial beta-oxidation and ATP generation) with fullerene (which provides antioxidant protection). This combined formulation ensures that while ketone esters drive energy metabolism, the fullerene simultaneously protects against oxidative stress from free radicals, achieving both energy enhancement and antioxidant activity in one composition.

Inventive Principle:
Principle #5Merging (Combining)

3Object-affected harmful factors

If C60 fullerene is used, then antioxidant potency is improved, but solubility and bioavailability are worsened

Engineering Contradiction:
Improvefree radical neutralization potencyVSAvoidsolubility and bioavailability
Core Design Contradiction:
Object-affected harmful factorsVSEase of operation

Solution Approach 1:

The patent uses ketone esters as intermediary substances that improve the solubility and bioavailability of C60 fullerene. Ketone esters act as a carrier medium that facilitates the dissolution of the hydrophobic fullerene in aqueous environments and enhances its absorption and transport in the biological system. This intermediary approach allows the potent but poorly soluble fullerene to deliver its antioxidant effects effectively in vivo.

Inventive Principle:
Principle #24Intermediary (Mediator)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The composition effectively neutralizes free radicals, boosts energy levels, and promotes anti-aging effects, including slowing or reversing aging, while improving overall health and longevity.

Implementation Method 1

Buckminsterfullerene is a fullerene with the formula C60. It has a cage-like fused-ring structure (truncated icosahedron) that resembles a soccer ball, made of twenty hexagons and twelve pentagons, with a carbon atom at each vertex of each polygon and a bond along each polygon edge. Due to its 30 carbon double bonds, 60-carbon fullerene is a powerful and recyclable antioxidant that neutralizes harmful free radicals.

Methodology Applied
Scientific EffectAntioxidant activity: Oxidation

Implementation Method 2

Moussa et al., teach using fullerene partially dissolved in a lipid carrier to prolong the life span in rats.

Methodology Applied
Scientific EffectLipid carrier transport: Solvation

Data Source

PatentUS12478599B2Nutraceutical composition comprising C60 and ketone esters
Publication Date: 2025.11.25 CHAMPIE MAX
  • US12478599B2 patent drawing
  • US12478599B2 patent drawing
  • US12478599B2 patent drawing

AI summary

An anti-oxidative, energy-boosting, and anti-aging nutraceutical composition containing fullerene substituted with functional groups, a medium chain triglyceride (preferably black seed oil), and the composition optionally includes one or more energy molecules not bound to the fullerene. Preferred functional groups and energy molecules include beta-hydroxybutyrate (more preferably D-beta-hydroxybutyrate) and carboxylic acids (e.g., caprylic acid and/or capric acid).