Cadaver Meniscus Implant for Hand Joint Reconstruction

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Solution Overview

Problem

Synthetic joint implants used for reconstructing damaged or arthritic joints in the hand are prone to infection, loosening, and breakage over time, leading to persistent pain and the need for follow-up surgeries.

Innovation Solution

The use of cadaver meniscus tissue, which is resilient and spongy, is employed for joint reconstruction by harvesting it from the knee, preparing the affected joint surfaces, and securing the meniscus tissue using sutures or fibrin glue to create a durable and biointegrated implant that can be revascularized and integrated into the joint.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If synthetic joint implants are used for joint reconstruction, then joint function can be restored, but the implants are prone to infection, loosening, and breakage over time

Engineering Contradiction:
Improveimplant durabilityVSAvoidinfection and loosening risk
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The invention changes the material parameter from synthetic (silicone, pyrolytic carbon) to biological (meniscus tissue), fundamentally altering the implant's interaction with the body. This biological material is less prone to infection and loosening while maintaining mechanical functionality for joint reconstruction

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The invention uses composite construction by combining meniscus tissue with sutures or fibrin glue to create a durable implant assembly. This composite approach integrates biological materials that work together to provide both structural support and biocompatibility, reducing the harmful effects associated with traditional synthetic implants

Inventive Principle:
Principle #40Composite materials

2Duration of action of stationary object

If synthetic joint implants are used, then joint reconstruction is achieved, but the implants may loosen or break over time requiring follow-up surgeries

Engineering Contradiction:
Improveimplant lifespanVSAvoidfollow-up surgery time
Core Design Contradiction:
Duration of action of stationary objectVSLoss of time

Solution Approach 1:

The invention changes the material composition from synthetic to biological meniscus tissue, which has the advantage of being biocompatible and less likely to degrade or loosen over time. This extends the effective lifespan of the implant and reduces the need for revision surgeries

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The meniscus tissue implant can be harvested from the patient's own body (autograft) or from a cadaver (allograft), and it integrates with the host tissue over time. This self-integrating property eliminates the need for additional fixation hardware and reduces follow-up surgical interventions

Inventive Principle:
Principle #25Self-service

3Reliability

If meniscus tissue is used for joint reconstruction, then biocompatibility and integration are improved, but the implantation process becomes more complex

Engineering Contradiction:
Improvebiointegration capabilityVSAvoidimplantation procedure complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The invention changes the material state from synthetic to biological meniscus tissue, which requires different handling and implantation techniques. The tissue must be harvested, processed, and implanted with care to maintain its structural integrity and promote integration, increasing procedural complexity but improving biocompatibility

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The invention uses sutures or fibrin glue as intermediary materials to secure the meniscus tissue implant to the joint surfaces. These intermediaries facilitate the integration of the biological tissue with the host tissue while managing the complexity of the implantation process

Inventive Principle:
Principle #24Intermediary (Mediator)

Data Source

PatentUS10905558B2Meniscus for joint reconstruction
Publication Date: 2021.02.02 CEDARS SINAI MEDICAL CENT
  • US10905558B2 patent drawing
  • US10905558B2 patent drawing
  • US10905558B2 patent drawing

AI summary

The invention provides treatment methods of using meniscus to repair injured and/or arthritic joints, for example, small hand joints including but not limited to radiocarpal, metacarpophalangeal, and interphalangeal joints. The invention also provides various implants made of meniscus for injured and/or arthritic joints.