Liquid Caffeine Composition With NALT for Room-Temperature Solubility
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Solution Overview
Problem
Existing caffeine formulations have low active ingredient concentrations, leading to single-dose consumption and safety concerns, with caffeine solubility decreasing from boiling water to room temperature, and Rhodiola rosea ingestion methods being inconvenient and delayed.
Innovation Solution
A composition combining caffeine with N-Acetyl-L-Tyrosine (NALT) and Rhodiola rosea extract, where NALT increases caffeine solubility at room temperature, and the inclusion of phenylpropanoids like rosavin and salidroside mitigates caffeine's adverse effects, with a process involving heating and cooling cycles to achieve stable, high caffeine concentrations.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Quantity of substance
If caffeine concentration is increased to provide sufficient energy-boosting effect, then the energy boost is improved, but safety concerns increase due to negative effects of caffeine on the body
Solution Approach 1:
The patent combines caffeine with other ingredients (such as L-theanine, B-vitamins, and adaptogens) to create a composite formulation that maintains high caffeine concentration while mitigating its negative effects through synergistic interactions between components
Solution Approach 2:
The patent introduces intermediary substances like L-theanine and adaptogens that act as mediators to buffer the harmful effects of high-dose caffeine, allowing the beneficial energy-boosting effects to be maintained while reducing side effects
2Quantity of substance
If caffeine solubility is increased in boiling water, then the concentration is improved, but the solubility decreases when the solution returns to room temperature
Solution Approach 1:
The patent changes the chemical parameters of the solution by adding substances that alter caffeine's solubility characteristics, enabling high concentration to be maintained across a broader temperature range including room temperature
Solution Approach 2:
The patent utilizes controlled phase transition processes, dissolving caffeine at elevated temperatures and then maintaining stability through the presence of other ingredients that prevent precipitation during cooling to room temperature
3Reliability
If Rhodiola rosea is consumed in traditional forms (tincture, capsule, or pill), then the health benefits are provided, but the onset of effects is delayed and convenience is reduced
Solution Approach 1:
The patent replaces traditional mechanical ingestion methods (swallowing pills or capsules) with an oral spray delivery system that utilizes mucosal absorption, eliminating the need for digestive breakdown and providing faster onset of effects
Solution Approach 2:
The patent uses the oral mucosa as an intermediary absorption pathway that bypasses the gastrointestinal tract and first-pass metabolism, enabling rapid delivery of Rhodiola rosea active ingredients to the bloodstream
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The synergy between caffeine and NALT results in significantly elevated caffeine solubility and stability at room temperature, allowing for efficient, compact energy ingestion, while Rhodiola rosea mitigates caffeine crashes and provides fast-onset benefits.
Implementation Method 1
tyrosine or NALT, (e.g. in some cases, to accelerate the reaction, preferably when exposed to heat), reacts with caffeine, substantially increasing caffeine's solubility
Implementation Method 2
applying a heating-mixing-cooling cycle to the water-caffeine-NALT liquid, the heating-mixing-cooling cycle comprising heating the liquid to boiling
Implementation Method 3
thoroughly mixing the liquid while it cools to room temperature
Data Source
AI summary
A liquid composition for use as a consumable stimulant; it has a consumable liquid solvent comprising water; caffeine at a concentration of at least 0.04 g/mL once dissolved in the consumable liquid solvent; and a tyrosine-based compound, wherein the presence of the tyrosine-based compound results in an increased solubility of the caffeine in the consumable liquid solvent. A method of increasing the solubility of caffeine.