Calcium Zeolite Hemostatic Agent for Traumatic Wound Bleeding Control
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Solution Overview
Problem
Existing blood clotting materials are ineffective in severe wounds, difficult to apply and remove, and can cause undesirable side effects, especially in situations where medical aid is not readily available.
Innovation Solution
A composition comprising a binder and a zeolite with adjusted calcium content, which reduces heat transfer and promotes rapid blood clotting by applying the zeolite to the wound, either in paste, gel, or powder form, or incorporated into a bandaging system.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If conventional blood clotting materials are applied to severe wounds, then some bleeding control is achieved, but they are ineffective for traumatic wounds and cause undesirable side effects
Solution Approach 1:
The patent modifies the calcium content parameter of zeolite to a specific range (75-83 wt%) to optimize blood clotting effectiveness while reducing harmful exothermic effects. This parameter adjustment resolves the contradiction by achieving reliable hemostasis in severe wounds without the undesirable side effects of excessive heat generation.
Solution Approach 2:
The invention uses composite materials combining zeolite with binders (such as cellulose, starch, or gelatin) to create a material that is both highly effective for traumatic wounds and easy to apply. The composite structure maintains the hemostatic properties of zeolite while adding applicability benefits from the binder system.
2Reliability
If existing blood clotting materials are used, then some hemostatic effect is achieved, but they are difficult to apply and remove
Solution Approach 1:
By combining zeolite with appropriate binders, the patent creates a composite material that maintains strong hemostatic effect while significantly improving ease of application. The binder system allows the material to be applied as a paste or powder that adheres to wound tissue, and can be easily removed after clotting occurs.
Solution Approach 2:
The invention employs disposable applications where the zeolite-binder composition is applied, performs its hemostatic function, and then removed or discarded. This approach prioritizes ease of operation by eliminating the need for complex removal procedures while maintaining reliable hemostatic effect.
3Productivity
If zeolite is applied to blood, then blood clotting is promoted, but exothermic effects cause temperature increase and discomfort
Solution Approach 1:
The patent carefully controls the calcium content parameter of zeolite within the range of 75-83 wt% to optimize the balance between blood clotting rate and heat generation. This parameter adjustment reduces the exothermic effect while maintaining high productivity in blood clotting, thereby minimizing temperature increase and patient discomfort.
4Reliability
If specialized equipment and trained personnel are used for severe bleeding, then effective hemostasis can be achieved, but such aid is not readily available in remote areas or battlefields
Solution Approach 1:
The zeolite-based composition is designed for self-service application by trained first responders or even untrained individuals in remote areas. The material requires no specialized equipment for application, can be stored without special conditions, and provides reliable hemostasis independently of complex medical infrastructure, thereby achieving both reliability and adaptability.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The solution effectively stops or minimizes bleeding quickly, reduces discomfort by minimizing temperature increase, and is easily applied and removed, making it suitable for use in remote or battlefield situations.
Implementation Method 1
When bleeding occurs, the fibrinogen reacts with water and thrombin (an enzyme) to form fibrin, which is insoluble in blood and polymerizes to form clots
Implementation Method 2
adjusting a calcium content of the zeolite/binder combination with a calcium-containing compound such that upon application of the composition to a wound, a heat of hydration is reduced and thereby the heat transferred to tissue surrounding the wound is reduced
Data Source
AI summary
A composition for promoting the formation of clots in blood comprises a binder and a zeolite disposed in the binder, the zeolite having an adjusted calcium content. A method of forming a blood-clotting composition comprises the steps of providing a zeolite, combining the zeolite with a binder, and adjusting a calcium content of the zeolite to have an amount of calcium such that upon application of the composition to a wound, a heat of hydration is reduced and thereby heat transferred to the wound is reduced. A method of clotting blood flowing from a wound comprises the steps of applying a zeolite to the wound and maintaining the zeolite in contact with the wound for a predetermined amount of time. The zeolite preferably has an adjusted calcium content and is capable of producing a controllable blood clotting effect on the wound.