Calendula Sulfur Wound Compound for Infection Control

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Solution Overview

Problem

Current wound healing products often keep wounds too moist, leading to increased susceptibility to infections and prolonged healing times, and there is a need for alternative treatments for exercise-induced pulmonary hemorrhage and other conditions in mammals.

Innovation Solution

A method using a wound healer compound comprising Calendula officinalis, sublimed sulfur, and Tea Tree Oil in a topical or oral pharmaceutical carrier to promote rapid and proper wound healing, reduce inflammation, and treat conditions like EIPH, ulcers, and anhydrosis.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If conventional wound healing products are used to maintain wound moisture, then wound hydration is improved, but susceptibility to infection increases and healing time is prolonged

Engineering Contradiction:
Improvewound healing effectivenessVSAvoidinfection susceptibility
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent converts the harmful effect of excessive moisture (which causes infection) into a beneficial effect by using sulfur and calendula extract to create an optimal moist environment that promotes healing while preventing infection. The sulfur specifically addresses the harmful moisture accumulation by providing antimicrobial action while maintaining necessary hydration for tissue regeneration.

Inventive Principle:
Principle #22Blessing in disguise (Convert harm into benefit)

Solution Approach 2:

The patent combines multiple active ingredients (sulfur, calendula extract, and other components) in a composite formulation that works synergistically. Sulfur provides antimicrobial protection and moisture regulation, while calendula extract promotes tissue regeneration and reduces inflammation, together creating a balanced wound healing environment that avoids the pitfalls of single-ingredient products.

Inventive Principle:
Principle #40Composite materials

2Reliability

If conventional wound healing products are used, then wound coverage is achieved, but healing time is prolonged

Engineering Contradiction:
Improvewound protectionVSAvoidhealing duration
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The patent applies sulfur and calendula extract to the wound before complete epithelialization occurs, preparing the wound bed in advance for faster healing. The sulfur creates an antimicrobial barrier early in the healing process, preventing infection that would delay healing, while calendula extract stimulates collagen production and tissue regeneration from the outset, reducing overall healing time.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent changes the chemical and biological parameters of the wound environment by introducing sulfur (which alters moisture content and microbial population) and calendula extract (which changes inflammatory response and tissue regeneration rates). These parameter changes accelerate the healing process while maintaining adequate protection.

Inventive Principle:
Principle #35Parameter changes

3Reliability

If sulfur is applied to wounds to prevent infection, then antimicrobial protection is improved, but odor and patient comfort deteriorate

Engineering Contradiction:
Improveantimicrobial effectivenessVSAvoidodor
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent merges sulfur with calendula extract and other ingredients to create a combined formulation where the unpleasant odor of sulfur is masked by the aromatic properties of calendula and other components. The combination maintains the antimicrobial effectiveness of sulfur while improving patient acceptability and comfort through the pleasant scent and soothing properties of the additional ingredients.

Inventive Principle:
Principle #5Merging (Combining)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The compound accelerates wound healing, reduces inflammation and pain, and effectively prevents and treats hemorrhaging, ulcers, and other conditions by enhancing blood flow and providing antimicrobial properties.

Implementation Method 1

This study demonstrated that calendula sped up the wound-healing process by increasing blood flow to the affected area and promoting the production of collagen proteins.

Methodology Applied
Scientific EffectBlood flow enhancement:

Implementation Method 2

Flowers of sulfur or sublimed sulfur are a sulfur powder that is a very popular ingredient in herbal remedies around the world. It was used since ancient times as a laxative, antiseptic and disinfectant.

Methodology Applied
Scientific EffectAntimicrobial action:

Implementation Method 3

Tea tree oil was selected for both its fragrance as well as its medicinal properties that are considered beneficial when applied topically which include antibacterial, antifungal, antiviral, and antiseptic properties.

Methodology Applied
Scientific EffectAntibacterial action:

Implementation Method 4

The calendula flower is known to possess unique properties and assist in wound healing, reduce inflammation, soothe and soften skin

Methodology Applied
Scientific EffectAnti-inflammatory action:

Data Source

PatentUS8709501B1Method for treating wounds for mammals, wound healer compound, and method of manufacturing thereof
Publication Date: 2014.04.29 JANSEN BEVERLY
  • US8709501B1 patent drawing
  • US8709501B1 patent drawing
  • US8709501B1 patent drawing

AI summary

A composition and method of use for treating wounds of mammals comprising an effective amount of the plant extracts Calendula officinalis and sublimed sulfur in a topical pharmaceutical carrier and or tea tree oil. The unique combination of these active plant extracts treats any type of wound effectively and immediately by increasing granulation at the site of the wound, promoting metabolism of proteins and collagen, inducing new cell growth, stopping bleeding, minimizing pain, and providing anti-bacterial activity. The present invention also provides a calendula composition to be administered orally to a mammal to alleviate EIPH or bleeding. The present invention also provides a calendula composition to alleviate the negative effects of inflammation due to stress, to treat muscle pulls and joints, to improve the eating regimen of high performance mammals, to treat mastitis, anhydrosis, and treat or prevent an ulcer in the stomach or duodenum of a mammalian patient.