Calibration Strip Filters for Fast Optical Deviation Correction
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Solution Overview
Problem
Conventional in vitro diagnostics devices suffer from optical deviations due to LED variations, leading to inconsistent test results and delayed calculations when using clinical specimens, control solutions, and pigments for calibration.
Innovation Solution
A calibration strip for in vitro diagnostics devices featuring a strip body with multiple cells and filters of varying optical densities, along with a filter unit and a bar code plate, allows for rapid calibration without liquids, ensuring consistent measurement values across devices.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If conventional calibration methods using clinical specimens, control solutions, and pigments are used, then calibration data can be obtained, but measurement deviation increases and calibration time is delayed
Solution Approach 1:
The patent uses a disposable calibration strip with pre-installed filters having known optical densities instead of reusable liquid calibration solutions. The calibration strip is a single-use component that eliminates the need for preparing and handling liquid calibration solutions, thereby reducing calibration time while maintaining measurement precision through the use of standardized filter elements with certified optical properties
Solution Approach 2:
The patent replaces the liquid-based calibration system with a solid-state filter system. Instead of using liquid calibration solutions that require pumping, handling, and disposal, the invention uses solid filters with predetermined optical densities that are directly mounted on the calibration strip, simplifying the calibration process and reducing time while improving measurement consistency
2Measurement precision
If multiple filters with different optical densities are used in the calibration strip, then measurement precision is improved, but device complexity increases
Solution Approach 1:
The calibration strip is divided into multiple independent measurement regions, each containing a filter with a specific optical density. This segmentation allows each region to independently correct for different aspects of optical deviation, improving overall measurement precision while keeping each individual filter element simple and standardized in design
Solution Approach 2:
Different filters with specific optical densities are placed in different locations on the calibration strip according to the specific calibration requirements of each measurement channel. This local optimization ensures that each measurement region receives the appropriate calibration reference, improving precision without requiring all filters to be present in all locations
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The calibration strip reduces detection time and ensures reliable, consistent results by using solid-state filters, minimizing deviations and enabling quick calibration across multiple devices.
Implementation Method 1
a filter unit including first filters and second filters which are disposed in the plurality of cells... the first filters and the second filters may have different optical densities
Data Source
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AI summary
The present invention relates to an improved calibration strip for an in vitro diagnostic device, the calibration strip having been improved so as to shorten calibration time and allow rapid determination of a calibration value without having to use a pigmented liquid. The calibration strip, which attaches to an in vitro diagnostic device, comprises: a strip body having a plurality of cells through which light generated from the in vitro diagnostic device passes when attached thereto; and a filter unit comprising first and second filters that are sequentially placed in respective cells and irradiated by the light that has passed through the plurality of cells.