Neural Network Interpretability via Class Activation Mapping

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Solution Overview

Problem

Deep learning models in medical image analysis lack interpretability, making it difficult for clinicians to understand the decision-making process and identify key areas for further investigation, which hinders their ability to make informed clinical decisions.

Innovation Solution

A computer-implemented method that calculates numeric values representing the influence of different regions of a medical image and non-image data elements on the output of a neural network, using techniques like Class Activation Mapping and Ablation CAM, to generate indicators that highlight the most contributory causes of the output, thereby providing clinicians with valuable information for assessment and decision-making.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If deep learning techniques are used for medical image analysis, then classification accuracy is improved, but interpretability deteriorates

Engineering Contradiction:
Improveclassification accuracyVSAvoidinterpretability
Core Design Contradiction:
Measurement precisionVSLoss of information

Solution Approach 1:

The patent introduces Class Activation Mapping (CAM) as an intermediary technique that generates heatmaps visualizing which image regions most influenced the deep learning model's classification decision. This mediator bridges the gap between the black-box deep learning model and human understanding, allowing clinicians to interpret model decisions without compromising classification accuracy

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent extracts and highlights only the most relevant regions from the medical image that contributed to the classification outcome. By taking out and emphasizing these critical areas through heatmaps, the system provides interpretability by showing clinicians exactly which parts of the image drove the model's decision

Inventive Principle:
Principle #2Taking out (Extraction)

2Device complexity

If deep learning models process only medical images, then processing simplicity is maintained, but diagnostic completeness deteriorates

Engineering Contradiction:
Improveprocessing simplicityVSAvoiddiagnostic completeness
Core Design Contradiction:
Device complexityVSLoss of information

Solution Approach 1:

The patent merges multiple data sources including medical images, patient demographics, clinical history, and laboratory results into a unified deep learning analysis framework. This combination allows the model to leverage diverse diagnostic information while maintaining a cohesive processing architecture that enhances diagnostic completeness without excessive complexity

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The patent creates a multi-functional deep learning system that can process various types of medical data (images, text, numerical values) through a single integrated model. This universal approach enables comprehensive diagnosis by handling multiple data modalities simultaneously, improving diagnostic completeness while avoiding the need for separate specialized systems

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Productivity

If clinicians rely solely on deep learning outputs, then decision efficiency is improved, but clinical judgment deterioration occurs

Engineering Contradiction:
Improvedecision efficiencyVSAvoidclinical judgment
Core Design Contradiction:
ProductivityVSEase of operation

Solution Approach 1:

The patent implements feedback mechanisms where Class Activation Mapping heatmaps are presented to clinicians alongside model predictions. This visual feedback allows clinicians to verify whether the model's decision aligns with their own assessment of the image, maintaining clinical judgment while benefiting from the efficiency of automated analysis

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The patent performs preliminary analysis using the deep learning model to generate initial diagnoses and highlight suspicious regions before the clinician makes the final decision. This preliminary action filters and prioritizes information for the clinician, improving decision efficiency while allowing clinical judgment to override or refine the automated suggestions

Inventive Principle:
Principle #10Preliminary action

Data Source

PatentUS20240420461A1Contextualizing the analysis of medical images
Publication Date: 2024.12.19 KONINKLIJKE PHILIPS NV
  • US20240420461A1 patent drawing
  • US20240420461A1 patent drawing
  • US20240420461A1 patent drawing

AI summary

A mechanism for providing additional information about a medical image analysis process. A neural network is used to process a medical image, and non-image data elements, to generate an output. An influence of different regions of the medical image and of the non-image data elements to an output of the neural network or intermediate layer output (of the neural network) is determined.