Camphorquinone Pharmaceutical Composition for Liver Fat Reduction

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Solution Overview

Problem

Current treatments for metabolic diseases such as obesity, diabetes, dyslipidemia, fatty liver, and arteriosclerosis are inadequate and often come with side effects, necessitating the development of new materials that can effectively prevent or treat these conditions without adverse effects.

Innovation Solution

A pharmaceutical and food composition containing camphorquinone or its pharmaceutically/sitologically acceptable salts, which modulate gene expression and metabolic pathways, reducing fat accumulation and improving glucose tolerance, thereby preventing or treating metabolic diseases.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If existing drugs for treating metabolic diseases are used, then treatment effects are achieved, but side effects occur

Engineering Contradiction:
Improvetreatment effectVSAvoidside effects
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent extracts and utilizes natural compounds (camphorquinone from photopolymerizers, curcumin from turmeric, resveratrol from grapes, quercetin from onions, and their derivatives) to treat metabolic diseases. These naturally derived compounds provide therapeutic effects while avoiding the side effects associated with conventional synthetic drugs, directly resolving the contradiction between treatment efficacy and harmful side effects.

Inventive Principle:
Principle #2Taking out (Extraction)

2Reliability

If conventional treatment methods are used for metabolic diseases, then disease symptoms are addressed, but satisfactory treatment results are not achieved

Engineering Contradiction:
Improvetreatment satisfactionVSAvoidtreatment effectiveness
Core Design Contradiction:
ReliabilityVSProductivity

Solution Approach 1:

The patent employs composite formulations combining multiple natural compounds (camphorquinone, curcumin, resveratrol, quercetin, and their derivatives) to treat metabolic diseases. This composite approach leverages the synergistic effects of different compounds to achieve satisfactory treatment results that conventional single-approach methods fail to deliver, addressing both treatment satisfaction and effectiveness.

Inventive Principle:
Principle #40Composite materials

Data Source

PatentUS12370152B2Pharmaceutical composition for preventing or treating metabolic diseases
Publication Date: 2025.07.29 IND ACADEMIC COOP FOUND CHOSUN UNIV
  • US12370152B2 patent drawing
  • US12370152B2 patent drawing
  • US12370152B2 patent drawing

AI summary

A method for preventing or treating metabolic diseases includes administering a composition including a compound represented by Formula 1 or a pharmaceutically acceptable salt thereof to a subject in need thereof. Thereby, it is possible to inhibit increases in body weight and liver fat weight due to a high-calorie diet, and decrease an accumulation of fat in the liver tissue, as well as modulate gene expression related to fat metabolism, and ultimately exhibit excellent preventive and therapeutic effects on metabolic diseases.