Topical Cannabidiol Preparation with Ozonized Oils

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Solution Overview

Problem

Existing dermatological preparations using cannabinoid substances like cannabidiol face challenges with absorption, necessitating high doses to achieve effective anti-wrinkle action, which is economically unsustainable.

Innovation Solution

A preparation combining synthetic cannabidiol with terpenes and ozonized unsaturated oils to enhance skin absorption, recreating the phytocomplex environment, utilizing ozonation to stabilize and increase the penetration of cannabidiol.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If the dose of cannabidiol is increased to achieve effective anti-wrinkle action, then the effectiveness is improved, but the economic sustainability deteriorates

Engineering Contradiction:
ImproveeffectivenessVSAvoidcost
Core Design Contradiction:
ReliabilityVSQuantity of substance

Solution Approach 1:

The patent changes the physical-chemical parameters of the preparation by incorporating ozonized unsaturated oils, which modify the absorption characteristics of cannabidiol. This allows achieving effective anti-wrinkle action at lower doses by improving bioavailability and skin penetration, thus resolving the contradiction between effectiveness and cost.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent creates a composite preparation combining synthetic cannabidiol with terpenes and ozonized unsaturated oils. This composite formulation enhances the absorption and effectiveness of cannabidiol, allowing lower doses to achieve the same therapeutic effect, thereby reducing overall cost while maintaining reliability.

Inventive Principle:
Principle #40Composite materials

2Reliability

If the dose of cannabidiol is increased to achieve effective anti-wrinkle action, then the effectiveness is improved, but the preparation complexity deteriorates

Engineering Contradiction:
ImproveeffectivenessVSAvoidpreparation complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

By modifying the absorption parameters through ozonization of unsaturated oils, the patent achieves better effectiveness at lower doses. This parameter change simplifies the preparation process compared to formulating high-dose preparations, as less active ingredient handling and more complex dosing regimens are required.

Inventive Principle:
Principle #35Parameter changes

3Stability of the object's composition

If plant extraction is used to obtain cannabidiol, then the phytocomplex environment is preserved, but the presence of THC causes legal restrictions

Engineering Contradiction:
Improvephytocomplex environmentVSAvoidlegal restrictions
Core Design Contradiction:
Stability of the object's compositionVSObject-affected harmful factors

Solution Approach 1:

The patent extracts only the beneficial cannabidiol component from the cannabis plant through synthesis, leaving behind the problematic THC. This selective extraction approach preserves the therapeutic effects of cannabidiol while eliminating the legal restrictions associated with THC presence, maintaining compliance with cosmetic regulations.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

Instead of using natural plant extraction, the patent synthesizes cannabidiol to create a copy of the active component without the associated legal issues. This synthetic approach replicates the beneficial effects of plant-derived cannabidiol while avoiding the presence of THC that would trigger legal restrictions.

Inventive Principle:
Principle #26Copying

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The preparation effectively increases cannabidiol absorption, providing anti-wrinkle benefits and treating dermatitis and skin inflammation, while avoiding the legal restrictions associated with THC extraction.

Implementation Method 1

unsaturated oils capable of increasing the cutaneous absorption of cannabidiol, said oils comprising one or more ozonized oily components

Methodology Applied
Scientific EffectOzonation: Ozone

Implementation Method 2

cannabidiol is present in combination with terpenes, biomolecules made up of multiples of the isoprenic unit, obtained in biological systems by the reaction of several units of IPP (isopentenyl pyrophosphate) and DMAPP (dimethylallyl pyrophosphate), which have the function of enhancing the active ingredient

Methodology Applied
Scientific EffectPhytocomplex enhancement:

Data Source

PatentEP3934621B1Preparation for topical use for dermatological treatments
Publication Date: 2025.06.25 HUG RES LABS SRL
  • EP3934621B1 patent drawing
  • EP3934621B1 patent drawing

AI summary

Preparation for topical use for dermatological treatments comprising Cannabidiol as the main active ingredient. In addition, Cannabidiol is provided in association with one or more ingredients chosen from the terpenes group.