Cannabinoid Fluorophore Tags for Low-Toxicity Optical Labeling

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Solution Overview

Problem

Existing optical compositions lack versatility and are often costly, toxic, or require complex synthesis, limiting their applications in various use scenarios.

Innovation Solution

Development of cannabinoid fluorophores with fluorescent properties, derived from natural sources, which can be used as tags or compounds in diverse applications, including biomedical imaging, textile dyeing, and electronic devices, offering a safer and more efficient alternative to synthetic fluorophores.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If known optical compositions are used, then optical properties are achieved, but cost increases and versatility decreases

Engineering Contradiction:
ImproveversatilityVSAvoidcost
Core Design Contradiction:
Adaptability or versatilityVSQuantity of substance

Solution Approach 1:

The cannabinoid fluorophore is designed to serve multiple functions across diverse applications including biomedical imaging, textile dyeing, electronic devices, and fabric care compositions. This single compound replaces multiple specialized optical materials, achieving versatility while maintaining cost-effectiveness through natural derivation rather than complex synthetic routes

Inventive Principle:
Principle #6Universality (Multi-functionality)

2Reliability

If synthetic fluorophores are used, then fluorescent properties are achieved, but toxicity increases

Engineering Contradiction:
Improvefluorescent propertiesVSAvoidtoxicity
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent utilizes naturally occurring cannabinoid fluorophores that can be derived from plant sources, replacing expensive and potentially toxic synthetic fluorophores. The natural origin provides inherent biocompatibility and reduced toxicity while maintaining reliable fluorescent properties for imaging and labeling applications

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

Solution Approach 2:

The chemical structure of the cannabinoid fluorophore is modified through derivatization to optimize fluorescent properties while maintaining non-toxicity. By adjusting molecular parameters such as substitution patterns and chain lengths, the compound achieves desired optical characteristics without introducing harmful synthetic elements

Inventive Principle:
Principle #35Parameter changes

3Ease of manufacture

If complex synthesis methods are used, then optical compositions are produced, but manufacturing complexity increases

Engineering Contradiction:
Improveproduction simplicityVSAvoidsynthesis complexity
Core Design Contradiction:
Ease of manufactureVSDevice complexity

Solution Approach 1:

The patent extracts fluorescent cannabinoid compounds directly from plant sources or obtains them through simple isolation processes, bypassing complex multi-step synthetic routes. This extraction approach significantly simplifies manufacturing while producing optically active compositions suitable for various applications

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

Instead of synthesizing fluorophores from basic chemical building blocks through complex pathways, the invention inverts the approach by isolating pre-formed fluorescent cannabinoids from natural sources. This reverse strategy reduces synthesis complexity and eliminates the need for elaborate chemical manufacturing processes

Inventive Principle:
Principle #13The other way round (Inversion)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The cannabinoid fluorophores provide a cost-effective, non-toxic, and thermally stable solution for a wide range of applications, enhancing safety and efficacy in medical imaging and industrial uses while being naturally fluorescent and CNS active.

Implementation Method 1

cannabinoid fluorophore

Methodology Applied
Scientific EffectFluorescence: Fluorescence

Data Source

PatentUS12480074B2Natural and synthetic cannabinoids as fluorescent tags; compositions, methods, and applications
Publication Date: 2025.11.25 UNIV OF CONNECTICUT
  • US12480074B2 patent drawing
  • US12480074B2 patent drawing
  • US12480074B2 patent drawing

AI summary

Disclosed are fluorescent tags comprising a cannabinoid fluorophore and compositions comprising the fluorescent tags.