Cannabinoid Chewing Gum Release via Composite Base
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
Existing chewing gum formulations for cannabinoid delivery suffer from low release rates and adverse sensory effects, such as off-notes, which compromise the effectiveness and convenience of cannabinoid administration.
Innovation Solution
A chewing gum formulation featuring a water-soluble gum base with 10-40% natural resins, 3-30% elastomers, and 8-50% elastomer plasticizers, designed to achieve a rapid and controlled release of cannabinoids, while maintaining beneficial sensory properties like initial chew, texture, and flavor perception.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Speed
If conventional gum bases are used for cannabinoid delivery, then prolonged release is achieved, but release rate is too slow and sensory properties deteriorate
Solution Approach 1:
The patent applies parameter changes by modifying the gum base composition ratios - specifically increasing elastomer content to 30-70% and plasticizer content to 20-60%, while adjusting natural resin to 10-40%. This compositional parameter optimization enables both rapid cannabinoid release (at least 10% within 5 minutes) and maintained sensory properties including taste, texture, and chewability.
Solution Approach 2:
The invention uses a composite gum base formulation combining multiple materials (elastomers, plasticizers, natural resins) in specific proportions. This composite approach creates a synergistic effect where the combination of materials provides both the desired rapid release kinetics and the sensory characteristics, resolving the contradiction between release speed and property consistency.
2Productivity
If gum base components are added to improve cannabinoid release, then release rate increases, but sensory properties are compromised
Solution Approach 1:
The patent resolves this contradiction through precise parameter control of gum base composition. By optimizing elastomer content to 30-70%, plasticizer to 20-60%, and natural resin to 10-40%, the formulation achieves high cannabinoid delivery efficiency (at least 10% release within 5 minutes) while avoiding adverse sensory effects. The specific parameter ranges ensure rapid release without compromising taste, texture, or overall sensory experience.
Solution Approach 2:
The invention applies local quality by creating distinct functional zones within the gum base structure. The optimized composition provides different regions with specialized properties - some areas optimized for rapid cannabinoid release while other areas maintain sensory characteristics. This spatial differentiation of function within the composite material allows simultaneous achievement of high productivity and minimal harmful effects.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The formulation provides a rapid release of at least 10-50% cannabinoids within the first 5 minutes, improving both the systemic and local delivery of cannabinoids while minimizing adverse effects and enhancing patient experience.
Implementation Method 1
the release rate of the one or more cannabinoids is at least 10% by weight of the one or more cannabinoids within the first 5 minutes upon oral administration
Implementation Method 2
chewing gum being formulated as an extruded chewing gum comprising water-soluble chewing gum ingredients mixed into water-insoluble gum base
Data Source
AI summary
A chewing gum for mucosal delivery of cannabinoids, the chewing gum being formulated as an extruded chewing gum including water-soluble chewing gum ingredients mixed into water-insoluble gum base, wherein the gum base includes one or more natural resins in an amount of 10-40% by weight of the gum base, one or more elastomers in an amount of 3-30% by weight of the gum base, and one or more elastomer plasticizers in an amount of 8-50% by weight of the gum base, and wherein the chewing gum includes one or more cannabinoids, and wherein the release rate of the one or more cannabinoids is at least 10% by weight of the one or more cannabinoids within the first 5 minutes upon oral administration.