Cannabinoid Chewing Gum Composition for Release and Sensorics
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Solution Overview
Problem
Existing chewing gum formulations for delivering cannabinoids face challenges in achieving appropriate release properties and sensorics, such as rapid absorption, adverse side effects, and compromised texture and flavor, particularly when combined with polyvinyl acetate and vinyl laurate-vinyl acetate copolymers.
Innovation Solution
A chewing gum formulation with a gum base comprising natural resins (10-40% by weight), elastomers (3-30% by weight), and polyvinyl acetate elastomer plasticizers (8-50% by weight) without vinyl laurate-vinyl acetate copolymer, ensuring homogeneous distribution and unbound form of cannabinoids, which enhances release and sensorics properties.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If conventional gum bases are used in chewing gum with cannabinoids, then the chewing gum can be manufactured, but the release properties of cannabinoids are compromised
Solution Approach 1:
The patent modifies the gum base composition by specifying precise parameter ranges: natural resins (10-40% by weight), elastomers (3-30% by weight), and elastomer plasticizers (8-50% by weight). This systematic parameter optimization resolves the contradiction by achieving reliable cannabinoid release through controlled composition rather than complex formulations.
Solution Approach 2:
The patent creates a composite gum base material combining natural resins, elastomers, and elastomer plasticizers in specific proportions. This composite approach improves cannabinoid release properties by leveraging the synergistic effects of different material components while maintaining manageable formulation complexity.
2Reliability
If conventional gum bases are used in chewing gum with cannabinoids, then the chewing gum can be manufactured, but the sensorics properties are compromised
Solution Approach 1:
The patent optimizes sensorics properties by controlling gum base parameters: natural resins (10-40%), elastomers (3-30%), and elastomer plasticizers (8-50%). These parameter adjustments improve texture, flavor perception, and sweetness perception without requiring overly complex compositions.
Solution Approach 2:
The patent applies local quality by optimizing specific regions of the gum base composition for different functions: natural resins for texture and mouthfeel, elastomers for elasticity, and elastomer plasticizers for flavor release. This targeted optimization improves overall sensorics without increasing overall complexity.
3Speed
If cannabinoids are administered by inhalation or smoking, then rapid blood absorption is achieved, but adverse side effects and safety issues occur
Solution Approach 1:
The patent introduces chewing gum as an intermediary delivery system between traditional inhalation methods and oral ingestion. The gum base matrix acts as a controlled release medium, providing faster absorption than swallowing pills while avoiding the harmful effects of combustion and rapid lung absorption.
Solution Approach 2:
The patent converts the typically slow release characteristic of oral ingestion into a beneficial controlled release profile. By using the gum base matrix, the formulation achieves sustained release that avoids the harmful rapid absorption of inhalation while maintaining therapeutic effectiveness.
4Strength
If vinyl laurate-vinyl acetate copolymer is used in the gum base, then the gum base has good elastic properties, but the release and sensorics properties of cannabinoids are compromised
Solution Approach 1:
The patent removes vinyl laurate-vinyl acetate copolymer from the gum base composition despite its elastic benefits. This extraction eliminates the negative impact on cannabinoid release and sensorics properties while compensating for elastic properties through alternative elastomer selections.
Solution Approach 2:
The patent combines natural resins, elastomers, and elastomer plasticizers in a unified gum base formulation. This merging creates a synergistic system that achieves both elastic properties and improved cannabinoid release/sensorics properties, replacing the problematic copolymer with a cooperative combination of components.
Data Source
AI summary
The present invention relates to a chewing gum for mucosal delivery of cannabinoids, the chewing gum being formulated as an extruded chewing gum comprising water-soluble chewing gum ingredients mixed into water-insoluble gum base, wherein the gum base comprising one or more natural resins in an amount of 10-40% by weight of the gum base, one or more elastomers in an amount of 3-30% by weight of the gum base, and one or more elastomer plasticizers in an amount of 8- 50% by weight of the gum base, and wherein the one or more elastomer plasticizers comprise one or more polyvinyl acetate elastomer plasticizers in an amount of 8-50% by weight of the gum base, and wherein the chewing gum comprises one or more cannabinoids.