Cannabinoid Topical Composition with Lanolin and Squalane

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Solution Overview

Problem

Current dermal wound and injury treatments lack effectiveness in addressing various types and severities of wounds, with existing products having clinical and treatment limitations.

Innovation Solution

A topical composition combining pharmacologically effective amounts of lanolin or its derivatives, extracted vegetable oils like squalane, and cannabinoids, such as CBD and THC, which enhance penetration and provide antimicrobial and therapeutic benefits.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If existing wound treatment products are used, then basic wound care is provided, but they lack effectiveness in addressing various types and severities of wounds due to clinical and treatment limitations

Engineering Contradiction:
Improvetreatment effectivenessVSAvoidapplicability to various wound types
Core Design Contradiction:
ReliabilityVSAdaptability or versatility

Solution Approach 1:

The topical composition is designed to treat multiple types of dermal wounds and injuries (lacerations, abrasions, contusions, burns, surgical incisions, infections, sores) with a single formulation, making the product universally applicable across various wound types and severities while maintaining reliable treatment effectiveness

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The composition combines multiple active ingredients (cannabinoids, lanolin, vegetable oils, plant oils) into a composite topical formulation that leverages the synergistic effects of each component to enhance both treatment reliability and versatility across different wound types

Inventive Principle:
Principle #40Composite materials

2Object-generated harmful factors

If lanolin is used as a base, then emollient properties and moisturization are provided, but penetration of active ingredients into the skin is limited

Engineering Contradiction:
Improvedryness and skin irritationVSAvoidpenetration rate of cannabinoids
Core Design Contradiction:
Object-generated harmful factorsVSSpeed

Solution Approach 1:

Penetration enhancers are introduced as intermediary substances that facilitate the transfer of cannabinoids from the lanolin base through the skin barrier, mediating between the emollient base and the active ingredients to achieve both moisturization and enhanced penetration

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The formulation modifies physical-chemical parameters such as viscosity, solubility, and molecular size by incorporating specific vegetable oils and plant oils, thereby optimizing the penetration rate of cannabinoids while maintaining the emollient properties of lanolin

Inventive Principle:
Principle #35Parameter changes

3Reliability

If higher concentrations of cannabinoids are used, then therapeutic benefits are enhanced, but risk of adverse effects and irritation increases

Engineering Contradiction:
Improvetherapeutic benefitVSAvoidskin irritation and adverse effects
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The composition optimizes the concentration parameters of cannabinoids within a specific range (0.05-15 wt%) and adjusts accompanying ingredients (lanolin 40-85 wt%, vegetable oils 1-25 wt%, plant oils 1-20 wt%) to achieve maximum therapeutic benefit while staying below the threshold of adverse effects and skin irritation

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The formulation distributes cannabinoids uniformly throughout the topical composition matrix, ensuring localized control of concentration at the application site, which maximizes therapeutic effects on the wound area while minimizing systemic absorption and potential adverse effects

Inventive Principle:
Principle #3Local quality

4Reliability

If multiple ingredients are combined to enhance penetration and therapy, then treatment efficacy is improved, but formulation complexity and manufacturing difficulty increase

Engineering Contradiction:
Improvetreatment efficacyVSAvoidformulation complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

Multiple functional ingredients (cannabinoids for therapy, lanolin for emollience, vegetable oils for penetration, plant oils for stability) are merged into a single integrated topical formulation, achieving enhanced treatment efficacy while consolidating multiple functions into one product

Inventive Principle:
Principle #5Merging (Combining)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The composition effectively treats dermal wounds by releasing cholesterol from lanolin, enhancing cannabinoid penetration with squalane and meadowfoam seed oil, promoting skin healing and rejuvenation while addressing various skin disorders.

Implementation Method 1

the cannabinoids release cholesterol contained in the lanolin releasing the cholesterol to topically penetrate and treat the wound

Methodology Applied
Scientific EffectRelease:

Implementation Method 2

enhancing cannabinoid penetration with squalane and meadowfoam seed oil

Methodology Applied
Scientific EffectPenetration enhancement: Permeation

Data Source

PatentUS20240041901A1Wound treatment topical composition containing cannabinoids
Publication Date: 2024.02.08 TF HLDG LLC
  • US20240041901A1 patent drawing
  • US20240041901A1 patent drawing
  • US20240041901A1 patent drawing

AI summary

A topical composition for dermal wounds or injuries comprising lanolin or derivatives thereof, one or more extracted vegetable oils, one or more extracted plant oils, and one or more cannabinoids. The cannabinoids used in the topical composition may be selected cannabinoids such as CBD and/or analogs and derivatives, THC and/or analogs and derivatives, or mixtures thereof. The extracted vegetable oils and plant oils used in the topical composition may be squalane, meadowfoam seed oil, or a mixture thereof. These components used in the topical composition may be naturally derived from vegetables, plants, or animals. The topical composition has effective pharmacological activity to care for or treat dermal wounds or injuries and may be used to care for or treat a human or an animal.