Cannabinoid Pouch Water-Soluble Matrix Release
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Solution Overview
Problem
Current methods for administering cannabinoids, such as smoking, result in rapid and unpredictable absorption, making it difficult to manage dosage and leading to undesirable side effects, particularly for medical use where precise dosing is crucial.
Innovation Solution
A pouch design featuring a powdered matrix composition with a water-soluble carrier that facilitates a fast and complete release of cannabinoids, allowing for controlled and predictable delivery, potentially incorporating sugar alcohols and release modifiers like metallic stearates to manage the release profile.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Speed
If smoking is used to administer cannabinoids, then rapid absorption into the blood is achieved, but the absorption becomes unpredictable and side effects increase
Solution Approach 1:
The patent changes the physical and chemical parameters of the cannabinoid delivery system by using a water-soluble carrier material and controlling the particle size distribution (D10, D50, D90 values) of the powdered composition. This allows for predictable dissolution rates and absorption kinetics, eliminating the unpredictable absorption associated with smoking while maintaining rapid delivery through optimized solubility and particle characteristics.
2Ease of operation
If smoking is used to administer cannabinoids, then administration is achieved, but the method has side effects and is difficult to manage
Solution Approach 1:
The patent replaces the mechanical combustion process of smoking with a dissolution-based delivery system. The water-soluble powdered composition dissolves in saliva or water, providing a controlled release mechanism that eliminates harmful combustion byproducts while allowing precise control over dosage and administration timing through the physical properties of the powder formulation.
3Productivity
If a water-soluble carrier is used in the powdered matrix composition, then fast and complete release of cannabinoids is achieved, but the complexity of formulation increases
Solution Approach 1:
The patent manages formulation complexity by carefully controlling specific parameters of the water-soluble carrier and powdered composition, including particle size distribution (D10, D50, D90), water solubility characteristics, and carrier-to-cannabinoid ratio. These parameter optimizations enable fast and complete release without requiring overly complex formulation strategies, as the release kinetics are primarily driven by the physical properties of the powder rather than complex chemical mechanisms.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Enables a precise and predictable delivery of cannabinoids, ensuring a complete release within a short time frame, providing a steep concentration gradient for effective absorption and intuitive confirmation of dosage completion, thus addressing the challenges of unpredictable absorption and side effects associated with smoking.
Implementation Method 1
a powdered matrix composition comprising a water-soluble composition
Implementation Method 2
the rapid absorption into the blood via the lung
Data Source
AI summary
A pouch designed for administration of an active ingredient in the oral cavity is disclosed, the pouch containing an amount of one or more cannabinoids. Also, pouches for use as a medicament, for use in alleviation of pain, and for use in mitigation of appetite deficiency are disclosed. Further, a method of alleviation of pain and a method of mitigation of appetite deficiency using the pouch are disclosed.