Cannabinoid Composition Ratios to Reduce THC-Induced Anxiety

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Solution Overview

Problem

Existing cannabis products with THC often cause anxiety and paranoia in users, and there is a desire for lower THC content while maintaining beneficial effects.

Innovation Solution

Compositions comprising THC and cannabigerol (CBG) in specific weight ratios, along with optional terpenes, are formulated to reduce THC-induced anxiety and provide a different intoxicating effect, including smokeable, edible, and beverage forms.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Quantity of substance

If THC content is increased to provide beneficial effects, then potency is improved, but anxiety and paranoia are induced

Engineering Contradiction:
ImproveTHC contentVSAvoidanxiety and paranoia
Core Design Contradiction:
Quantity of substanceVSObject-affected harmful factors

Solution Approach 1:

CBG acts as an intermediary substance that modulates THC's effects. The patent combines CBG with THC in specific ratios (1:1 to 5:1 CBG:THC) where CBG serves as a mediator that reduces the harmful psychoactive effects of THC while preserving or enhancing the beneficial effects, thereby resolving the contradiction between potency and harmful effects

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent creates a composite cannabinoid formulation combining multiple cannabinoids (CBG, THC, and optionally CBD, CBC, CBN) in specific ratios. This composite approach allows the synergistic interaction between different cannabinoids to achieve the desired therapeutic effects while mitigating the harmful effects associated with high THC content alone

Inventive Principle:
Principle #40Composite materials

2Object-affected harmful factors

If THC content is reduced to eliminate anxiety, then harmful effects are reduced, but beneficial effects are diminished

Engineering Contradiction:
Improveanxiety and paranoiaVSAvoidpotency
Core Design Contradiction:
Object-affected harmful factorsVSQuantity of substance

Solution Approach 1:

The patent changes the compositional parameters by introducing CBG and adjusting the cannabinoid ratio. Instead of simply reducing THC, the formulation modifies the overall cannabinoid profile parameters (CBG:THC ratio, inclusion of other cannabinoids) to maintain potency while reducing harmful effects, thereby resolving the contradiction between eliminating harm and preserving benefit

Inventive Principle:
Principle #35Parameter changes

3Device complexity

If single cannabinoid formulations are used, then simplicity is maintained, but user experience variability increases

Engineering Contradiction:
Improveformulation simplicityVSAvoidintoxication predictability
Core Design Contradiction:
Device complexityVSReliability

Solution Approach 1:

The patent establishes homogeneous and consistent ratios of CBG to THC (specifically 1:1 to 5:1 ranges) across the formulation. This standardized homogeneous composition ensures predictable and reliable effects, reducing the variability experienced with single cannabinoid or inconsistent formulations while maintaining formulation simplicity through defined ratios

Inventive Principle:
Principle #33Homogeneity

Data Source

PatentUS20250367220A1Compositions comprising cannabinoids and methods of preparation and use thereof
Publication Date: 2025.12.04 NEW GROWTH BRANDS INC

AI summary

Compositions that include cannabinoids other than tetrahydrocannabinol (THC), such as cannabigerol (CBG) in combination with tetrahydrocannabinol (THC) or formulated to be combined with THC, and methods of preparation and use thereof are described. The compositions may be useful to reduce the risk of THC-induced anxiety and/or to produce a different intoxicating effect compared to THC alone.