Cannabis Gel Formulations for Bioavailability and Dosing
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Solution Overview
Problem
Current cannabis formulations for mammals and avians lack optimal dosing and long-term effect data, are costly, and do not efficiently achieve beneficial effects, necessitating the development of formulations that minimize dosages while ensuring safety and efficacy.
Innovation Solution
Cannabis-containing compositions in gel formulations, including natural or synthetic cannabidiol, terpenes, and flavonoids, with excipients like vegetable oil and microcrystalline cellulose, suitable for various administration routes, including oral, topical, and transdermal, to enhance bioavailability and therapeutic effects.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If cannabis formulations are administered to achieve beneficial therapeutic effects, then therapeutic efficacy is improved, but cost increases and dosage optimization is limited
Solution Approach 1:
The patent applies parameter changes by modifying the physical and chemical parameters of cannabis formulations through gel-based delivery systems, liposomal encapsulation, and nanotechnology. These parameter changes improve bioavailability and therapeutic efficacy while reducing the required dosage and cost of administration
2Reliability
If cannabis formulations are administered to achieve beneficial therapeutic effects, then therapeutic efficacy is improved, but safe dosing information is limited
Solution Approach 1:
The patent applies preliminary action by conducting comprehensive pre-clinical studies, pharmacokinetic analysis, and safety assessments before clinical administration. This preliminary research establishes safe dosing ranges, optimal formulations, and expected outcomes, reducing the loss of dosing information during actual therapeutic use
3Ease of operation
If traditional cannabis formulations are used, then administration is simple, but bioavailability is low and therapeutic outcomes are limited
Solution Approach 1:
The patent applies composite materials by combining cannabis extracts with gel bases, liposomal structures, and nanocarriers. These composite formulations maintain ease of administration through various delivery routes while dramatically improving bioavailability and therapeutic outcomes compared to traditional formulations
Data Source
AI summary
The present disclosure application relates to cannabis-containing compositions comprising at least one cannabinoid, provided in a gel formulation. The compositions may include cannabidiol. The source of the cannabidioid may be cannabis, a cannabis extract, or an industrial hemp oil extract. Methods of treating and/or reducing symptoms of an inflammatory response and/or inflammation are described, comprising administering to a subject in need thereof the disclosed compositions.