Cannabis Stem Fermentation for Anti-Wrinkle Cosmetics

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Current cosmetic products are inadequate in addressing photoaging-induced wrinkles due to limitations in using cannabis components regulated by law, and existing treatments do not effectively alleviate skin damage caused by UV exposure.

Innovation Solution

A cosmetic composition utilizing a Lacticaseibacillus casei (KCTC 3109) fermentation product of cannabis stems as an active ingredient, which is derived from non-regulated cannabis stem parts, effectively alleviates wrinkles caused by photoaging through fermentation processes.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If cannabis components (leaves, flowers, resin) are used in cosmetic products, then anti-wrinkle and photoaging effects are improved, but legal restrictions and regulatory limitations occur due to narcotic control laws

Engineering Contradiction:
Improveanti-wrinkle effectVSAvoidlegal availability
Core Design Contradiction:
ReliabilityVSAdaptability or versatility

Solution Approach 1:

The patent extracts and utilizes only the stem portion of cannabis, separating it from the narcotic-controlled components (leaves, flowers, resin containing THC, CBD, CBN). This allows legal production while maintaining cosmetic benefits through fermentation of stem-specific compounds

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent changes the chemical parameters of cannabis stem through microbial fermentation, transforming raw stem material into a fermented extract with enhanced bioactive compounds. This parameter transformation creates a legally distinct product with improved anti-wrinkle efficacy

Inventive Principle:
Principle #35Parameter changes

2Ease of operation

If conventional cosmetic treatments are used for photoaging, then general skin care is provided, but effective alleviation of UV-induced skin damage and wrinkles is insufficient

Engineering Contradiction:
Improvecosmetic treatmentVSAvoidphotoaging amelioration effect
Core Design Contradiction:
Ease of operationVSReliability

Solution Approach 1:

The fermentation process transforms the chemical composition of cannabis stem extract, generating new bioactive compounds with enhanced UV protection and anti-wrinkle properties. This parameter change creates superior photoaging protection compared to conventional treatments

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The fermented extract combines multiple bioactive compounds produced during fermentation, creating a composite material with synergistic effects against UV damage, collagen degradation, and wrinkle formation

Inventive Principle:
Principle #40Composite materials

3Device complexity

If cannabis stem extract is used without fermentation, then simple formulation is achieved, but cytotoxicity is high and anti-wrinkle effect is limited

Engineering Contradiction:
Improveformulation processVSAvoidskin safety and efficacy
Core Design Contradiction:
Device complexityVSReliability

Solution Approach 1:

Fermentation fundamentally changes the chemical parameters of cannabis stem extract, reducing cytotoxic compounds while generating beneficial metabolites. This transformation improves both safety and efficacy despite added process complexity

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

Lactic acid bacteria serve as an intermediary agent that mediates the transformation of cannabis stem extract. The bacteria modify the extract's composition, reducing toxicity and enhancing anti-wrinkle activity through metabolic conversion

Inventive Principle:
Principle #24Intermediary (Mediator)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The composition significantly reduces cytotoxicity and enhances anti-wrinkle effects against UV light, providing a more effective solution for photoaging compared to other lactic acid bacteria, with potential applications in cosmetics, pharmaceuticals, and health functional foods.

Implementation Method 1

when the cannabis stem raw material or extract was fermented through lactic acid bacteria, wrinkles could be alleviated

Methodology Applied
Scientific EffectFermentation: Fermentation

Data Source

PatentUS20240366495A1Composition for ameliorating wrinkles using fermented extract of cannabis stem and preparation method thereof
Publication Date: 2024.11.07 KOREA INST OF SCI & TECH
  • US20240366495A1 patent drawing
  • US20240366495A1 patent drawing
  • US20240366495A1 patent drawing

AI summary

The present invention relates to a use of a fermentation product of Lacticaseibacillus casei of cannabis stems and an extract thereof for ameliorating skin wrinkles caused by photoaging, and to an anti-wrinkle cosmetic composition or pharmaceutical composition including the fermentation product.