Cannula Capture and Reinfusion for En-Bloc Clot Removal

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Solution Overview

Problem

Existing catheter-based treatments for removing undesirable materials from medium to large blood vessels and heart chambers are inefficient due to fragmentation and excessive blood loss, as they struggle to achieve complete en-bloc removal without significant fragmentation or excessive fluid loss.

Innovation Solution

A system and method using a cannula with a polymer wall, stepped distal end, and an expandable element to capture undesirable material en-bloc, combined with a pump for suction and a second cannula for reinfusion, along with a filter to minimize fluid loss and debris, allowing for continuous or intermittent suction and reinfusion.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If conventional catheter-based treatments are used to remove undesirable materials from medium to large blood vessels and heart chambers, then the treatment can be performed minimally invasively, but significant fragmentation occurs and excessive blood loss results

Engineering Contradiction:
Improveminimally invasive treatmentVSAvoidblood loss
Core Design Contradiction:
Ease of operationVSLoss of substance

Solution Approach 1:

The patent extracts the undesirable material (clot, tumor, or foreign body) en-bloc from the blood vessel or heart chamber using a specially designed catheter system with a basket or net structure that captures the material intact, preventing fragmentation and minimizing blood loss by removing only the target material without excessive aspiration of surrounding blood

Inventive Principle:
Principle #2Taking out (Extraction)

2Ease of operation

If conventional catheter-based treatments are used to remove undesirable materials from medium to large blood vessels and heart chambers, then the treatment can be performed minimally invasively, but complete en-bloc removal without significant fragmentation is difficult to achieve

Engineering Contradiction:
Improveminimally invasive treatmentVSAvoidcomplete en-bloc removal without fragmentation
Core Design Contradiction:
Ease of operationVSManufacturing precision

Solution Approach 1:

The patent employs a nested structure where a basket or net element is deployed from within the catheter shaft. The basket expands outward to envelop the undesirable material, capturing it intact. The catheter shaft then retracts to contain the captured material within the basket structure, enabling complete en-bloc removal without fragmentation while maintaining minimally invasive access

Inventive Principle:
Principle #7Nested doll (Nesting)

3Manufacturing precision

If larger catheters are used to remove material en-bloc from medium to large vessels, then complete removal is achieved, but excessive fluid loss and shock risk increase

Engineering Contradiction:
Improvecomplete en-bloc removalVSAvoidshock and bleeding risks
Core Design Contradiction:
Manufacturing precisionVSObject-affected harmful factors

Solution Approach 1:

The patent selectively extracts only the undesirable material (clot, tumor, or foreign body) using a basket or net structure that captures the target material while excluding surrounding blood. This selective extraction achieves complete en-bloc removal of the pathology while minimizing fluid loss and reducing shock and bleeding risks

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The catheter system applies local action at the site of the undesirable material, using a deployed basket or net structure that captures material locally without requiring large-scale aspiration. This localized approach removes the pathology completely while minimizing impact on surrounding blood volume, reducing shock and bleeding risks

Inventive Principle:
Principle #3Local quality

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Effectively removes undesirable materials such as blood clots, tumors, and foreign bodies from medium to large vessels and heart chambers with minimal fragmentation and fluid loss, improving patient outcomes by minimizing shock and bleeding risks.

Implementation Method 1

a pump, in fluid communication with the proximal end of the first cannula, so as to provide a sufficient suction force for removing the undesirable material from the site of interest

Methodology Applied
Scientific EffectSuction: Suction

Implementation Method 2

a filter device positioned in fluid communication with the first cannula so as to trap the undesirable material and remove it from the fluid flow

Methodology Applied
Scientific EffectFiltration: Filter (physical)

Data Source

PatentUS12496077B2Systems and methods for removing undesirable material within a circulatory system
Publication Date: 2025.12.16 ANGIODYNAMICS INC
  • US12496077B2 patent drawing
  • US12496077B2 patent drawing
  • US12496077B2 patent drawing

AI summary

The present invention relates generally to improved systems and methods for removing undesirable material residing in vessels. More specifically, the present invention relates to systems and methods for using at least one cannula to remove substantially en bloc, from a site of obstruction or interest, undesirable material without fragmentation and without excessive fluid loss.