Cannula Positioning Guide for Spinal Injection Accuracy

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Solution Overview

Problem

Current cannula systems face challenges in optimizing performance due to factors such as depth and volume of injection, fluidity and diffusion properties of therapeutic agents, anatomical sensitivity, and complexity of surgical procedures, leading to issues with backflow, placement accuracy, and ease of use.

Innovation Solution

The development of a cannula system with a proximal and distal region, featuring a delivery tube made from medical-grade materials like stainless steel or fused silica, a cannula positioning guide for precise placement, and a kit including an adhesive for secure attachment, enhancing accuracy, flexibility, and control during therapeutic agent delivery.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If a cannula system is used for delivering therapeutic agents to target tissue, then therapeutic delivery is achieved, but backflow occurs reducing delivery efficiency

Engineering Contradiction:
Improvetherapeutic delivery efficiencyVSAvoidbackflow
Core Design Contradiction:
ProductivityVSLoss of substance

Solution Approach 1:

The cannula system applies preliminary anti-action by incorporating a backflow prevention mechanism that counteracts the backflow force before it can significantly reduce therapeutic delivery efficiency. The system proactively addresses the backflow issue through design features that resist reverse flow, ensuring more complete drug delivery to the target tissue.

Inventive Principle:
Principle #9Preliminary anti-action

2Ease of operation

If surgical procedures are simplified for ease of use, then ease of operation improves, but placement accuracy may deteriorate

Engineering Contradiction:
Improveease of useVSAvoidplacement accuracy
Core Design Contradiction:
Ease of operationVSManufacturing precision

Solution Approach 1:

The cannula system introduces an intermediary positioning guide that mediates between the simplified surgical procedure and precise placement requirements. This guide component facilitates accurate cannula positioning without requiring complex surgical techniques, thus maintaining ease of operation while ensuring placement accuracy.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Manufacturing precision

If the cannula system includes additional components for improved control, then delivery precision improves, but device complexity increases

Engineering Contradiction:
Improvedelivery precisionVSAvoiddevice complexity
Core Design Contradiction:
Manufacturing precisionVSDevice complexity

Solution Approach 1:

The cannula system applies segmentation by dividing the delivery system into distinct functional components: the cannula itself, the positioning guide, and the delivery mechanism. This segmentation allows each component to be optimized for its specific function while maintaining overall system precision, without requiring all components to be present for basic operation.

Inventive Principle:
Principle #1Segmentation

Data Source

PatentUS20250090197A1Cannula system and use thereof
Publication Date: 2025.03.20 VOYAGER THERAPEUTICS INC
  • US20250090197A1 patent drawing
  • US20250090197A1 patent drawing
  • US20250090197A1 patent drawing

AI summary

The present disclosure relates to cannula systems for delivery of a therapeutic agent to parenchymal tissue of a target subject. In certain embodiments, the cannula system is for delivery of a therapeutic agent to parenchymal tissue in the spine of a target subject. In certain embodiments, the cannula system includes a cannula positioning guide (CPG) useful in the delivery of a therapeutic agent to a localized target tissue of a subject. The guide may be used in a surgical suite or during a surgical procedure.